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Erdheim-Chester Disease

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Tumors and Tumor-Like Lesions of Bone

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Abstract

Erdheim-Chester disease, or lipid granulomatosis, is a rare disorder characterized by the proliferation of histiocytes in bone and in extraosseous locations. It is thought perhaps to be a lipid storage disease, in which foamy lipid-laden histiocytes accumulate in the bone marrow. Extravasated lipid results in cholesterol granulomas and a fibroinflammatory reaction.

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Recommended Reading

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Author information

Authors and Affiliations

  1. Department of Pathology and Orthopaedic Surgery, Johns Hopkins Hospital, Baltimore, MD, USA

    Edward McCarthy MD

Authors
  1. Edward McCarthy MD
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Correspondence to Edward McCarthy MD .

Editor information

Editors and Affiliations

  1. Laboratory of Orthopaedic Pathology, Buenos Aires, Argentina

    Eduardo Santini-Araujo

  2. Laboratory of Orthopaedic Pathology, Buenos Aires, Argentina

    Ricardo K. Kalil

  3. Villa Erbosa Hospital, University of Bologna, Bologna, Italy

    Franco Bertoni

  4. Department of Pathology, Kyung Hee University Hospital, Seoul, Korea, Republic of (South Korea)

    Yong-Koo Park

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© 2015 Springer-Verlag London

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McCarthy, E. (2015). Erdheim-Chester Disease. In: Santini-Araujo, E., Kalil, R., Bertoni, F., Park, YK. (eds) Tumors and Tumor-Like Lesions of Bone. Springer, London. https://doi.org/10.1007/978-1-4471-6578-1_72

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  • DOI: https://doi.org/10.1007/978-1-4471-6578-1_72

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-6577-4

  • Online ISBN: 978-1-4471-6578-1

  • eBook Packages: MedicineMedicine (R0)

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