Abstract
Rabbits immunised with human HLA-B27 lymphocytes have been shown to react against antigens obtained from several Gram-negative microorganisms. Xenoantigens are widely distributed throughout nature and induce the formation of cross-reactive antibodies which may be involved in the pathogenesis of various diseases (Whittingham and Mackay 1977).
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Asherson GL, Holborow EJ. Autoantibody production in rabbits. VII. Autoantibodies to gut produced by injection of bacteria. Immunology. 1966;10:161–7.
Avakian H, Welsh J, Ebringer A, Entwistle CC. Ankylosing spondylitis, HLA-B27 and Klebsiella. II. Cross-reactivity studies with human tissue typing sera. Br J Exp Pathol. 1980;61:92–6.
Caffrey MFP, James DCO. Human lymphocyte antigen association in ankylosing spondylitis. Nature. 1973;242:121.
Damian RT. Molecular mimicry: antigen sharing by parasite and host and its consequences. Am Nat. 1964;98:129–49.
Ebringer A. The link between genes and disease. New Sci. 1978;79:865–7.
Festenstein H, Démant P. HLA and H-2. London: Edward Arnold; 1978.
Hirata AA, McIntire FC, Terasaki PI, Mittal KK. Crossreactions between human transplantation antigens and bacterial lipopolysaccharides. Transplantation. 1973;15:441–5.
Kaplan MH, Meyeserian M. An immunological crossreaction between Group A Streptococcal cells and human heart. Lancet. 1962;1:706–10.
Rowley D, Jenkin CR. Antigenic crossreaction between host and parasite as a possible cause of pathogenicity. Nature. 1962;193:151–4.
Whittingham S, Mackay IR. Tissue antigens: autoantigens, alloantigens xenoantigens and neoantigens. Aust N Z J Med. 1977;7:172–94.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2013 Springer-Verlag London
About this chapter
Cite this chapter
Ebringer, A., Ebringer, A. (2013). Molecular Mimicry Between HLA-B27 and Klebsiella Bacteria Investigated by Using Human Tissue Typing Sera. In: Ankylosing spondylitis and Klebsiella. Springer, London. https://doi.org/10.1007/978-1-4471-4300-0_5
Download citation
DOI: https://doi.org/10.1007/978-1-4471-4300-0_5
Published:
Publisher Name: Springer, London
Print ISBN: 978-1-4471-4299-7
Online ISBN: 978-1-4471-4300-0
eBook Packages: MedicineMedicine (R0)