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MRS of the Neonatal Brain: Abnormal Development and Neonatal Pathology

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MR Spectroscopy of Pediatric Brain Disorders

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Abstract

The most frequently encountered intracranial pathologies in the neonatal period include hemorrhage (e.g., germinal matrix/intraventricular hemorrhages, intraparenchymal hemorrhages or extraaxial hemorrhages), hypoxic–ischemic injuries (i.e., hypoxic–ischemic encephalopathy, stroke), and encephalopathy of prematurity, which includes both focal and diffuse injury to the developing white matter. Less frequently encountered are congenital malformations involving the cerebrum (e.g., diffuse migrational abnormalities, intrahemispheric cysts) or the posterior fossa (e.g., congenital aqueductal stenosis, chiari malformations), infections, trauma, tumors/masses, and early-onset metabolic disorders.

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Author information

Authors and Affiliations

  1. Brain and Creativity Institute and Dornsife Cognitive Neuroscience Imaging Center, University of Southern California, Los Angeles, CA, USA

    Jessica L. Wisnowski Ph.D.

  2. Division of Pediatric Neuroradiology, Department of Radiology, Children’s Hospital of Pittsburgh at UPMC, Pittsburgh, PA, USA

    Andre D. Furtado M.D.

  3. Department of Radiology, Children’s Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA, USA

    Niveditha Pinnamaneni B.A., B.S.

  4. Department of Pediatric Radiology, Children’s Hospital of Pittsburgh of UPMC, Pittsburgh, PA, USA

    Ashok Panigrahy M.D.

  5. Department of Radiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA

    Ashok Panigrahy M.D.

Authors
  1. Jessica L. Wisnowski Ph.D.
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  2. Andre D. Furtado M.D.
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  3. Niveditha Pinnamaneni B.A., B.S.
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  4. Ashok Panigrahy M.D.
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Editor information

Editors and Affiliations

  1. Keck School of Medicine, Dept. Radiology, University of Southern California, Zonal Avenue 1975, Los Angeles, 90089-9034, California, USA

    Stefan Blüml

  2. , Dept. of Pediatric Radiology, Children's Hospital of Pittsburg of UPMC, Penn Avenue 4401, Pittsburgh, 15224, Pennsylvania, USA

    Ashok Panigrahy

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Wisnowski, J.L., Furtado, A.D., Pinnamaneni, N., Panigrahy, A. (2013). MRS of the Neonatal Brain: Abnormal Development and Neonatal Pathology. In: Blüml, S., Panigrahy, A. (eds) MR Spectroscopy of Pediatric Brain Disorders. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-5864-8_20

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  • DOI: https://doi.org/10.1007/978-1-4419-5864-8_20

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