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Macrophage Polarization and Osteoclast Differentiation

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Rheumatoid Arthritis

Part of the book series: Methods in Molecular Biology ((MIMB,volume 2766))

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Abstract

Macrophages are a key player to regulate rheumatoid arthritis pathogenesis from onset to remission. They can alter innate functions under microenvironmental conditions. To understand heterogeneous functions of macrophages in rheumatoid arthritis, several activated statuses of macrophages should be mimicked in vitro. Here, we describe basic protocols for macrophage polarization and osteoclast differentiation.

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Author information

Authors and Affiliations

  1. Division of Medical Research Support, Advanced Research Support Center, Ehime University, Toon, Ehime, Japan

    Noritaka Saeki

  2. Division of Integrative Pathophysiology, Proteo-Science Center, Ehime University, Toon, Ehime, Japan

    Noritaka Saeki

  3. Department of Pathophysiology, Ehime University Graduate School of Medicine, Toon, Ehime, Japan

    Akihiro Nakata

Authors
  1. Noritaka Saeki
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  2. Akihiro Nakata
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Corresponding author

Correspondence to Noritaka Saeki .

Editor information

Editors and Affiliations

  1. Department of Pharmacology, Ehime University School of Medicine, Toon, Ehime, Japan

    Shuang Liu

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© 2024 The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature

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Saeki, N., Nakata, A. (2024). Macrophage Polarization and Osteoclast Differentiation. In: Liu, S. (eds) Rheumatoid Arthritis. Methods in Molecular Biology, vol 2766. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-3682-4_26

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  • DOI: https://doi.org/10.1007/978-1-0716-3682-4_26

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  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-3681-7

  • Online ISBN: 978-1-0716-3682-4

  • eBook Packages: Springer Protocols

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