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Web-Based Resources to Investigate Protease Function

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Proteases and Cancer

Part of the book series: Methods in Molecular Biology ((MIMB,volume 2747))

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Abstract

In 2001, the release of the first draft of the human genome marked the beginning of the Big Data era for biological sciences. Since then, the complexity of datasets generated by laboratories worldwide has increased exponentially. Public repositories such as the Protein Data Bank, which has exceeded the 200000 entries in 2023, have been instrumental not only to collect, organize, and distill this enormous research output but also to promote further research enterprises. The achievements of artificial intelligence programs such as AlphaFold would not have been possible without the collective efforts of countless researchers who made their work publicly available. Here, I provide a practical, but far from exhaustive, list of resources useful to investigate protease function.

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Acknowledgments

The Santamaria Lab is supported by the British Heart Foundation (FS/IBSRF/20/25032).

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Authors and Affiliations

  1. Department of Biochemical Sciences, School of Biosciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, UK

    Salvatore Santamaria

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  1. Salvatore Santamaria
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Correspondence to Salvatore Santamaria .

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Editors and Affiliations

  1. Department of Biochemical Sciences, School of Biosciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, UK

    Salvatore Santamaria

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© 2024 The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature

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Santamaria, S. (2024). Web-Based Resources to Investigate Protease Function. In: Santamaria, S. (eds) Proteases and Cancer. Methods in Molecular Biology, vol 2747. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-3589-6_1

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  • DOI: https://doi.org/10.1007/978-1-0716-3589-6_1

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  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-3588-9

  • Online ISBN: 978-1-0716-3589-6

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