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Gastrointestinal and Microbiome Profiling in Rodent Models of Neurological and Psychiatric Disorders

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Schizophrenia

Part of the book series: Methods in Molecular Biology ((MIMB,volume 2687))

Abstract

Mice and other rodent models have been widely used to understand the role of the gut microbiome in various neurological and psychiatric disorders. Here we describe a protocol to characterize the structural and functional phenotype of the rodent gut and to examine the gut microbiota composition through V4 16S rRNA gene sequencing and microbiome profiling. This protocol will have utility for those investigating the gut, and associated microbiota, in a wide range of different rodent models of human disorders.

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Correspondence to Anthony J. Hannan .

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© 2023 The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature

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Kong, G., Gubert, C., Hannan, A.J. (2023). Gastrointestinal and Microbiome Profiling in Rodent Models of Neurological and Psychiatric Disorders. In: Urigüen, L., Díez-Alarcia, R. (eds) Schizophrenia. Methods in Molecular Biology, vol 2687. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-3307-6_7

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  • DOI: https://doi.org/10.1007/978-1-0716-3307-6_7

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  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-3306-9

  • Online ISBN: 978-1-0716-3307-6

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