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Solid Lipid Nanoparticles for Drug Delivery

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Liposomes

Part of the book series: Methods in Molecular Biology ((MIMB,volume 2622))

Abstract

Solid lipid nanoparticles are promising carriers that allow for the delivery of poorly water-soluble drugs and have the potential to achieve sustained drug release or targeted delivery to the site of interest. Here we describe the preparation of solid lipid nanoparticles by forming a microemulsion at an elevated temperature which, upon cooling, yields a suspension of solid nanoparticles. This nanotemplate engineering method is inexpensive, reproducible, and easy to scale up.

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Author information

Authors and Affiliations

  1. School of Pharmacy, University of Connecticut, Storrs, CT, USA

    Wei-Chung Luo & Xiuling Lu

Authors
  1. Wei-Chung Luo
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  2. Xiuling Lu
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Corresponding author

Correspondence to Xiuling Lu .

Editor information

Editors and Affiliations

  1. School of Pharmacy, MCPHS University, Boston, MA, USA

    Gerard G.M. D'Souza

  2. School of Pharmacy, MCPHS University, Boston, MA, USA

    Hongwei Zhang

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© 2023 The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature

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Luo, WC., Lu, X. (2023). Solid Lipid Nanoparticles for Drug Delivery. In: D'Souza, G.G., Zhang, H. (eds) Liposomes. Methods in Molecular Biology, vol 2622. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-2954-3_12

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  • DOI: https://doi.org/10.1007/978-1-0716-2954-3_12

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  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-2953-6

  • Online ISBN: 978-1-0716-2954-3

  • eBook Packages: Springer Protocols

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