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In Vivo Imaging of Brown Adipose Tissue in Humans: FDG-PET/CT and Beyond

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Brown Adipose Tissue

Part of the book series: Methods in Molecular Biology ((MIMB,volume 2448))

Abstract

Positron emission tomography (PET) combined with computed tomography (CT) is used to detect brown adipose tissue (BAT) in humans. Function can be measured using different tracers, most typically with glucose analog 18F-fluoro-deoxyglucose (FDG). CT provides an anatomical reference, but this tool can be utilized for other purposes as well, such as indirect estimate of triglyceride content of the BAT. PET/CT measurements require sophisticated and highly specified devices, and manufacturer-dependent differences exist between different scanners. Therefore, complete device-specific instructions are not given in this article, but rather general guidelines which are important when human BAT is imaged using PET/CT.

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Correspondence to Kirsi A. Virtanen .

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Virtanen, K.A. (2022). In Vivo Imaging of Brown Adipose Tissue in Humans: FDG-PET/CT and Beyond. In: Guertin, D.A., Wolfrum, C. (eds) Brown Adipose Tissue. Methods in Molecular Biology, vol 2448. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-2087-8_18

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  • DOI: https://doi.org/10.1007/978-1-0716-2087-8_18

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  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-2086-1

  • Online ISBN: 978-1-0716-2087-8

  • eBook Packages: Springer Protocols

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