Abstract
Hair cells in cochlea and vestibular organs depend on the coordinated cell polarity to perform the normal auditory or balance function. The mouse inner ear is one of the ideal model to study planar cell polarity. In this chapter, we introduce a series of general experimental methods for studying planar cell polarity in the inner ear. The approaches presented here are also applicable to other organs with particular polarity phenotypes.
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Acknowledgments
This work was supported by funding to DR from the National Natural Science Foundation of China (NSFC) (81771017, 81570920, and 81970880), the “Zhuo-Xue Plan” of Fudan University to DR, and the Shanghai Outstanding Young Medical Talent Program to DR.
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Lyu, J., Qian, X., Chen, B., Ren, D. (2022). Methods to Investigate Cell Polarity of Inner Ear. In: Chang, C., Wang, J. (eds) Cell Polarity Signaling. Methods in Molecular Biology, vol 2438. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-2035-9_16
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DOI: https://doi.org/10.1007/978-1-0716-2035-9_16
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