Abstract
Small-angle scattering (SAS) is a technique commonly used in the soft matter sciences to characterize the structure of molecules self-assembling in solution. As such, it is suitable to study preparations of homogeneous liposomes to extract simple structural parameters such as radius and lipid bilayer thickness in solution. Here, we describe the preparation of liposomes for small-angle neutron scattering via extrusion and present the simplest way the resulting data can be modeled.
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Acknowledgments
The author is grateful to Michihiro Nagao, Paul Butler, Charles Cranfield and to many colleagues at NIST and ANSTO.
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Wood, K. (2022). Small-Angle Neutron Scattering of Liposomes: Sample Preparation to Simple Modeling. In: Cranfield, C.G. (eds) Membrane Lipids. Methods in Molecular Biology, vol 2402. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-1843-1_12
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DOI: https://doi.org/10.1007/978-1-0716-1843-1_12
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