Abstract
Development of molecularly imprinted solid-phase extraction (MISPE) sorbents for the removal of drugs from human urine is described. MISPE sorbents are synthesized through free radical polymerization mechanism and non-covalent imprinting approach. After the completion of the polymerization, bulk polymer is ground using an analytical mill and then wet-sieved. Later on, MISPE sorbent has been dry-packed into solid-phase extraction cartridges after the extraction of template drug molecule. Eluates from the cartridges are analyzed using a spectrophotometer or spectrofluorimeter for the determination of target analyte by referring to the calibration curves.
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Basan, H. (2021). Molecularly Imprinted Solid-Phase Extraction Sorbents for the Selective Extraction of Drugs from Human Urine. In: MartÃn-Esteban, A. (eds) Molecularly Imprinted Polymers. Methods in Molecular Biology, vol 2359. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-1629-1_10
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DOI: https://doi.org/10.1007/978-1-0716-1629-1_10
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Publisher Name: Humana, New York, NY
Print ISBN: 978-1-0716-1628-4
Online ISBN: 978-1-0716-1629-1
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