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Culture-Based Antimicrobial Susceptibility Testing for Helicobacter pylori

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Helicobacter Pylori

Part of the book series: Methods in Molecular Biology ((MIMB,volume 2283))

Abstract

Culture-based antimicrobial susceptibility testing is a crucial method for the management of Helicobacter pylori infection . It must follow the European Committee on Antimicrobial Susceptibility Testing (EUCAST) recommendations for fastidious microaerophilic bacteria, with some possible variation especially for the medium to be used. It is recommended to test six antibiotics by diffusion using strips charged with an antibiotic gradient in order to determine the minimum inhibitory concentrations (MICs). Two of these antibiotics, clarithromycin and levofloxacin, are more important because of frequent resistance which jeopardizes the success of the treatment.

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Correspondence to Francis Mégraud .

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Lehours, P., Mégraud, F. (2021). Culture-Based Antimicrobial Susceptibility Testing for Helicobacter pylori. In: Smith, S.M. (eds) Helicobacter Pylori. Methods in Molecular Biology, vol 2283. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-1302-3_6

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  • DOI: https://doi.org/10.1007/978-1-0716-1302-3_6

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  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-1301-6

  • Online ISBN: 978-1-0716-1302-3

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