Abstract
In this chapter, a catalog of the various types of bias that can affect the validity of clinical epidemiologic studies is presented. The biases are classified by stage of research: literature review and publication, design of the study and selection of subjects, execution of the intervention, measurement of exposures and outcomes, data analysis , and interpretation and publication. Definitions are provided for each type of bias listed.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Miettinen OS, Cook EF (1981) Confounding: essence and detection. Am J Epidemiol 114:593–603
Sackett DL (1979) Bias in analytic research. J Chron Dis 32:51–68
Delgado-RodrĂguez M, Llorca J (2004) Bias. J Epidemiol Comm Health 58(8):635–641
Porta M (1988) A dictionary of epidemiology, 5th edn. Oxford University Press, New York, NY
Gail M, Benichou J (2000) Encyclopedia of epidemiologic methods. Wiley, West Sussex, UK
Althubaiti A (2016) Information bias in health research: definition, pitfalls, and adjustment methods. J Multidiscip Healthc 4:211–217
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2021 Springer Science+Business Media, LLC, part of Springer Nature
About this protocol
Cite this protocol
Warden, G. (2021). Definitions of Bias in Clinical Research. In: Parfrey, P.S., Barrett, B.J. (eds) Clinical Epidemiology. Methods in Molecular Biology, vol 2249. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-1138-8_3
Download citation
DOI: https://doi.org/10.1007/978-1-0716-1138-8_3
Published:
Publisher Name: Humana, New York, NY
Print ISBN: 978-1-0716-1137-1
Online ISBN: 978-1-0716-1138-8
eBook Packages: Springer Protocols