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Functionalized Carbon Nanohorns as Drug Delivery Platforms

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Supramolecules in Drug Discovery and Drug Delivery

Part of the book series: Methods in Molecular Biology ((MIMB,volume 2207))

Abstract

Carbon nanohorns (CNHs) resembling a single-layered graphene sheet wrapped in a conical shape can be chemically modified in order to immobilize, carry, and release biologically active molecules. Here, we describe the major routes for the preparation of CNH-based drug delivery platforms, via covalent coupling and encapsulation, proficient to facilitate the design of sophisticated drug nanocarriers.

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Acknowledgments

Partial support by the project “National Infrastructure in Nanotechnology, Advanced Materials and Micro-/Nanoelectronics” (MIS 5002772) which is implemented under the “Reinforcement of the Research and Innovation Infrastructures,” funded by the Operational Program “Competitiveness, Entrepreneurship and Innovation” (NSRF 2014–2020) and co-financed by Greece and the European Union (European Regional Development Fund), is acknowledged.

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Authors and Affiliations

  1. National Hellenic Research Foundation, Theoretical and Physical Chemistry Institute, Athens, Greece

    Anastasios Stergiou & Nikos Tagmatarchis

Authors
  1. Anastasios Stergiou
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  2. Nikos Tagmatarchis
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Corresponding author

Correspondence to Nikos Tagmatarchis .

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Editors and Affiliations

  1. Department of Chemistry, National and Kapodistrian University of Athens, Zografou, Greece

    Thomas Mavromoustakos

  2. Department of Chemistry Section of Organic Chemistry and Biochemistry, University of Ioannina, Ioannina, Greece

    Andreas G. Tzakos

  3. Computational Biology and Molecular Simulations Laboratory Department of Biophysics, School of Medicine, Bahcesehir University, Istanbul, Turkey

    Serdar Durdagi

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Stergiou, A., Tagmatarchis, N. (2021). Functionalized Carbon Nanohorns as Drug Delivery Platforms. In: Mavromoustakos, T., Tzakos, A.G., Durdagi, S. (eds) Supramolecules in Drug Discovery and Drug Delivery. Methods in Molecular Biology, vol 2207. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-0920-0_2

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  • DOI: https://doi.org/10.1007/978-1-0716-0920-0_2

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  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-0919-4

  • Online ISBN: 978-1-0716-0920-0

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