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Endoscopic Diagnosis and Treatment of Esophageal Squamous Cell Carcinoma

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Esophageal Squamous Cell Carcinoma

Part of the book series: Methods in Molecular Biology ((MIMB,volume 2129))

Abstract

Esophageal squamous cell carcinoma (ESCC) is a deadly disease, partly because it is often diagnosed late in disease stage. An accurate early diagnosis by endoscopy could detect advanced carcinoma as well as curable dysplasia and early ESCC. This could save patients from incurable advanced malignancy. Important progress has been made in high-quality endoscopic diagnosis, including magnifying endoscopy, narrowband imaging, and other image enhancement, as well as in techniques in endoscopic resection. These emerging techniques will aid the early diagnosis of ESCC that lead to higher chance of curing the cancer.

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References

  1. Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M, Parkin DM, Forman D, Bray F (2015) Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer 136(5):E359–E386. https://doi.org/10.1002/ijc.29210

    Article  CAS  PubMed  Google Scholar 

  2. Lagergren J, Smyth E, Cunningham D, Lagergren P (2017) Oesophageal cancer. Lancet 390(10110):2383–2396. https://doi.org/10.1016/S0140-6736(17)31462-9

    Article  PubMed  Google Scholar 

  3. Smyth EC, Lagergren J, Fitzgerald RC, Lordick F, Shah MA, Lagergren P, Cunningham D (2017) Oesophageal cancer. Nat Rev Dis Primers 3:17048. https://doi.org/10.1038/nrdp.2017.48

    Article  PubMed  PubMed Central  Google Scholar 

  4. Prabhu A, Obi KO, Rubenstein JH (2014) The synergistic effects of alcohol and tobacco consumption on the risk of esophageal squamous cell carcinoma: a meta-analysis. Am J Gastroenterol 109(6):822–827. https://doi.org/10.1038/ajg.2014.71

    Article  PubMed  Google Scholar 

  5. Chiu PWY, Uedo N, Singh R, Gotoda T, Ng EKW, Yao K, Ang TL, Ho SH, Kikuchi D, Yao F, Pittayanon R, Goda K, Lau JYW, Tajiri H, Inoue H (2019) An Asian consensus on standards of diagnostic upper endoscopy for neoplasia. Gut 68(2):186–197. https://doi.org/10.1136/gutjnl-2018-317111

    Article  PubMed  Google Scholar 

  6. Kaltenbach T, Sano Y, Friedland S, Soetikno R, American Gastroenterological A (2008) American Gastroenterological Association (AGA) Institute technology assessment on image-enhanced endoscopy. Gastroenterology 134(1):327–340. https://doi.org/10.1053/j.gastro.2007.10.062

    Article  PubMed  Google Scholar 

  7. Lal N, Bhasin DK, Malik AK, Gupta NM, Singh K, Mehta SK (1992) Optimal number of biopsy specimens in the diagnosis of carcinoma of the oesophagus. Gut 33(6):724–726. https://doi.org/10.1136/gut.33.6.724

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Pech O, Gunter E, Dusemund F, Origer J, Lorenz D, Ell C (2010) Accuracy of endoscopic ultrasound in preoperative staging of esophageal cancer: results from a referral center for early esophageal cancer. Endoscopy 42(6):456–461. https://doi.org/10.1055/s-0029-1244022

    Article  CAS  PubMed  Google Scholar 

  9. Rampado S, Bocus P, Battaglia G, Ruol A, Portale G, Ancona E (2008) Endoscopic ultrasound: accuracy in staging superficial carcinomas of the esophagus. Ann Thorac Surg 85(1):251–256. https://doi.org/10.1016/j.athoracsur.2007.08.021

    Article  PubMed  Google Scholar 

  10. Yip HC, Chiu PW (2017) Endoscopic diagnosis and management of early squamous cell carcinoma of esophagus. J Thorac Dis 9(Suppl 8):S689–S696. https://doi.org/10.21037/jtd.2017.06.57

    Article  PubMed  PubMed Central  Google Scholar 

  11. Draganov PV, Wang AY, Othman MO, Fukami N (2019) AGA institute clinical practice update: endoscopic submucosal dissection in the United States. Clin Gastroenterol Hepatol 17(1):16–25 e11. https://doi.org/10.1016/j.cgh.2018.07.041

    Article  PubMed  Google Scholar 

  12. Barret M, Prat F (2018) Diagnosis and treatment of superficial esophageal cancer. Ann Gastroenterol 31(3):256–265. https://doi.org/10.20524/aog.2018.0252

    Article  PubMed  PubMed Central  Google Scholar 

  13. Muto M, Minashi K, Yano T, Saito Y, Oda I, Nonaka S, Omori T, Sugiura H, Goda K, Kaise M, Inoue H, Ishikawa H, Ochiai A, Shimoda T, Watanabe H, Tajiri H, Saito D (2010) Early detection of superficial squamous cell carcinoma in the head and neck region and esophagus by narrow band imaging: a multicenter randomized controlled trial. J Clin Oncol 28(9):1566–1572. https://doi.org/10.1200/JCO.2009.25.4680

    Article  PubMed  PubMed Central  Google Scholar 

  14. Shiozaki H, Tahara H, Kobayashi K, Yano H, Tamura S, Imamoto H, Yano T, Oku K, Miyata M, Nishiyama K et al (1990) Endoscopic screening of early esophageal cancer with the Lugol dye method in patients with head and neck cancers. Cancer 66(10):2068–2071. https://doi.org/10.1002/1097-0142(19901115)66:10<2068::aid-cncr2820661005>3.0.co;2-w

    Article  CAS  PubMed  Google Scholar 

  15. Dubuc J, Legoux J, Winnock M, Seyrig J, Barbier J, Barrioz T, Laugier R, Boulay G, Grasset D, Sautereau D, Grigoresco D, Butel J, Scoazec J, Ponchon T, Societe Francaise d’Endoscopie D (2006) Endoscopic screening for esophageal squamous-cell carcinoma in high-risk patients: a prospective study conducted in 62 French endoscopy centers. Endoscopy 38(7):690–695

    Article  CAS  PubMed  Google Scholar 

  16. McQuaid KR, Laine L (2008) A systematic review and meta-analysis of randomized, controlled trials of moderate sedation for routine endoscopic procedures. Gastrointest Endosc 67(6):910–923. https://doi.org/10.1016/j.gie.2007.12.046

    Article  PubMed  Google Scholar 

  17. Hiki N, Kaminishi M, Yasuda K, Uedo N, Honjo H, Matsuhashi N, Hiratsuka T, Sekine C, Nomura S, Yahagi N, Tajiri H, Suzuki H (2011) Antiperistaltic effect and safety of L-menthol sprayed on the gastric mucosa for upper GI endoscopy: a phase III, multicenter, randomized, double-blind, placebo-controlled study. Gastrointest Endosc 73(5):932–941. https://doi.org/10.1016/j.gie.2010.12.013

    Article  PubMed  Google Scholar 

  18. Fujishiro M, Kaminishi M, Hiki N, Oda I, Fujisaki J, Uedo N, Kaise M, Tanabe S, Iguchi M, Matsuhashi N, Nomura S, Tajiri H, Yahagi N, Suzuki H (2014) Efficacy of spraying l-menthol solution during endoscopic treatment of early gastric cancer: a phase III, multicenter, randomized, double-blind, placebo-controlled study. J Gastroenterol 49(3):446–454. https://doi.org/10.1007/s00535-013-0856-4

    Article  CAS  PubMed  Google Scholar 

  19. Chen HW, Hsu HC, Hsieh TY, Yeh MK, Chang WK (2014) Pre-medication to improve esophagogastroduodenoscopic visibility: a meta-analysis and systemic review. Hepato-Gastroenterology 61(134):1642–1648

    PubMed  Google Scholar 

  20. Araki K, Ohno S, Egashira A, Saeki H, Kawaguchi H, Sugimachi K (2002) Pathologic features of superficial esophageal squamous cell carcinoma with lymph node and distal metastasis. Cancer 94(2):570–575. https://doi.org/10.1002/cncr.10190

    Article  PubMed  Google Scholar 

  21. Yamashina T, Ishihara R, Nagai K, Matsuura N, Matsui F, Ito T, Fujii M, Yamamoto S, Hanaoka N, Takeuchi Y, Higashino K, Uedo N, Iishi H (2013) Long-term outcome and metastatic risk after endoscopic resection of superficial esophageal squamous cell carcinoma. Am J Gastroenterol 108(4):544–551. https://doi.org/10.1038/ajg.2013.8

    Article  PubMed  Google Scholar 

  22. Nakagawa K, Koike T, Iijima K, Shinkai H, Hatta W, Endo H, Ara N, Uno K, Asano N, Imatani A, Shimosegawa T (2014) Comparison of the long-term outcomes of endoscopic resection for superficial squamous cell carcinoma and adenocarcinoma of the esophagus in Japan. Am J Gastroenterol 109(3):348–356. https://doi.org/10.1038/ajg.2013.450

    Article  PubMed  Google Scholar 

  23. Merkow RP, Bilimoria KY, Keswani RN, Chung J, Sherman KL, Knab LM, Posner MC, Bentrem DJ (2014) Treatment trends, risk of lymph node metastasis, and outcomes for localized esophageal cancer. J Natl Cancer Inst 106(7):dju133. https://doi.org/10.1093/jnci/dju133

    Article  PubMed  Google Scholar 

  24. Hulscher JB, van Sandick JW, de Boer AG, Wijnhoven BP, Tijssen JG, Fockens P, Stalmeier PF, ten Kate FJ, van Dekken H, Obertop H, Tilanus HW, van Lanschot JJ (2002) Extended transthoracic resection compared with limited transhiatal resection for adenocarcinoma of the esophagus. N Engl J Med 347(21):1662–1669. https://doi.org/10.1056/NEJMoa022343

    Article  PubMed  Google Scholar 

  25. Yoshida T, Inoue H, Usui S, Satodate H, Fukami N, Kudo SE (2004) Narrow-band imaging system with magnifying endoscopy for superficial esophageal lesions. Gastrointest Endosc 59(2):288–295. https://doi.org/10.1016/s0016-5107(03)02532-x

    Article  PubMed  Google Scholar 

  26. Kumagai Y, Toi M, Inoue H (2002) Dynamism of tumour vasculature in the early phase of cancer progression: outcomes from oesophageal cancer research. Lancet Oncol 3(10):604–610

    Article  PubMed  Google Scholar 

  27. Inoue H, Honda T, Nagai K, Kawano T, Yoshino K, Takeshita K, Endo M (1997) Ultra-high magnification endoscopic observation of carcinoma in situ of the esophagus. Dig Endosc 9(1):16–18. https://doi.org/10.1111/j.1443-1661.1997.tb00453.x

    Article  Google Scholar 

  28. Inoue H, Kaga M, Ikeda H, Sato C, Sato H, Minami H, Santi EG, Hayee B, Eleftheriadis N (2015) Magnification endoscopy in esophageal squamous cell carcinoma: a review of the intrapapillary capillary loop classification. Ann Gastroenterol 28(1):41–48

    PubMed  PubMed Central  Google Scholar 

  29. Oyama T, Inoue H, Arima M, Momma K, Omori T, Ishihara R, Hirasawa D, Takeuchi M, Tomori A, Goda K (2017) Prediction of the invasion depth of superficial squamous cell carcinoma based on microvessel morphology: magnifying endoscopic classification of the Japan Esophageal Society. Esophagus 14(2):105–112. https://doi.org/10.1007/s10388-016-0527-7

    Article  PubMed  Google Scholar 

  30. Morita FH, Bernardo WM, Ide E, Rocha RS, Aquino JC, Minata MK, Yamazaki K, Marques SB, Sakai P, de Moura EG (2017) Narrow band imaging versus lugol chromoendoscopy to diagnose squamous cell carcinoma of the esophagus: a systematic review and meta-analysis. BMC Cancer 17(1):54. https://doi.org/10.1186/s12885-016-3011-9

    Article  PubMed  PubMed Central  Google Scholar 

  31. Nagami Y, Tominaga K, Machida H, Nakatani M, Kameda N, Sugimori S, Okazaki H, Tanigawa T, Yamagami H, Kubo N, Shiba M, Watanabe K, Watanabe T, Iguchi H, Fujiwara Y, Ohira M, Hirakawa K, Arakawa T (2014) Usefulness of non-magnifying narrow-band imaging in screening of early esophageal squamous cell carcinoma: a prospective comparative study using propensity score matching. Am J Gastroenterol 109(6):845–854. https://doi.org/10.1038/ajg.2014.94

    Article  PubMed  PubMed Central  Google Scholar 

  32. Sharma P, Wani S, Bansal A, Hall S, Puli S, Mathur S, Rastogi A (2007) A feasibility trial of narrow band imaging endoscopy in patients with gastroesophageal reflux disease. Gastroenterology 133(2):454–464; quiz 674. https://doi.org/10.1053/j.gastro.2007.06.006

    Article  PubMed  Google Scholar 

  33. Mori M, Adachi Y, Matsushima T, Matsuda H, Kuwano H, Sugimachi K (1993) Lugol staining pattern and histology of esophageal lesions. Am J Gastroenterol 88(5):701–705

    CAS  PubMed  Google Scholar 

  34. Dawsey SM, Fleischer DE, Wang GQ, Zhou B, Kidwell JA, Lu N, Lewin KJ, Roth MJ, Tio TL, Taylor PR (1998) Mucosal iodine staining improves endoscopic visualization of squamous dysplasia and squamous cell carcinoma of the esophagus in Linxian, China. Cancer 83(2):220–231

    Article  CAS  PubMed  Google Scholar 

  35. Lee YC, Wang CP, Chen CC, Chiu HM, Ko JY, Lou PJ, Yang TL, Huang HY, Wu MS, Lin JT, Hsiu-Hsi Chen T, Wang HP (2009) Transnasal endoscopy with narrow-band imaging and Lugol staining to screen patients with head and neck cancer whose condition limits oral intubation with standard endoscope (with video). Gastrointest Endosc 69(3 Pt 1):408–417. https://doi.org/10.1016/j.gie.2008.05.033

    Article  PubMed  Google Scholar 

  36. Takenaka R, Kawahara Y, Okada H, Hori K, Inoue M, Kawano S, Tanioka D, Tsuzuki T, Uemura M, Ohara N, Tominaga S, Onoda T, Yamamoto K (2009) Narrow-band imaging provides reliable screening for esophageal malignancy in patients with head and neck cancers. Am J Gastroenterol 104(12):2942–2948. https://doi.org/10.1038/ajg.2009.426

    Article  PubMed  Google Scholar 

  37. Kondo H, Fukuda H, Ono H, Gotoda T, Saito D, Takahiro K, Shirao K, Yamaguchi H, Yoshida S (2001) Sodium thiosulfate solution spray for relief of irritation caused by Lugol's stain in chromoendoscopy. Gastrointest Endosc 53(2):199–202. https://doi.org/10.1067/mge.2001.110730

    Article  CAS  PubMed  Google Scholar 

  38. Stevens PD, Lightdale CJ, Green PH, Siegel LM, Garcia-Carrasquillo RJ, Rotterdam H (1994) Combined magnification endoscopy with chromoendoscopy for the evaluation of Barrett’s esophagus. Gastrointest Endosc 40(6):747–749

    Article  CAS  PubMed  Google Scholar 

  39. Thuler FP, de Paulo GA, Ferrari AP (2004) Chemical esophagitis after chromoendoscopy with Lugol’s solution for esophageal cancer: case report. Gastrointest Endosc 59(7):925–926. https://doi.org/10.1016/s0016-5107(04)00173-7

    Article  PubMed  Google Scholar 

  40. Sreedharan A, Rembacken BJ, Rotimi O (2005) Acute toxic gastric mucosal damage induced by Lugol’s iodine spray during chromoendoscopy. Gut 54(6):886–887. https://doi.org/10.1136/gut.2004.061739

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  41. Sgourakis G, Gockel I, Lyros O, Hansen T, Mildenberger P, Lang H (2011) Detection of lymph node metastases in esophageal cancer. Expert Rev Anticancer Ther 11(4):601–612. https://doi.org/10.1586/era.10.150

    Article  PubMed  Google Scholar 

  42. Pech O, May A, Gunter E, Gossner L, Ell C (2006) The impact of endoscopic ultrasound and computed tomography on the TNM staging of early cancer in Barrett's esophagus. Am J Gastroenterol 101(10):2223–2229. https://doi.org/10.1111/j.1572-0241.2006.00718.x

    Article  PubMed  Google Scholar 

  43. Thosani N, Singh H, Kapadia A, Ochi N, Lee JH, Ajani J, Swisher SG, Hofstetter WL, Guha S, Bhutani MS (2012) Diagnostic accuracy of EUS in differentiating mucosal versus submucosal invasion of superficial esophageal cancers: a systematic review and meta-analysis. Gastrointest Endosc 75(2):242–253. https://doi.org/10.1016/j.gie.2011.09.016

    Article  PubMed  Google Scholar 

  44. Findlay JM, Bradley KM, Maile EJ, Braden B, Maw J, Phillips-Hughes J, Gillies RS, Maynard ND, Middleton MR (2015) Pragmatic staging of oesophageal cancer using decision theory involving selective endoscopic ultrasonography, PET and laparoscopy. Br J Surg 102(12):1488–1499. https://doi.org/10.1002/bjs.9905

    Article  CAS  PubMed  Google Scholar 

  45. Vazquez-Sequeiros E, Norton ID, Clain JE, Wang KK, Affi A, Allen M, Deschamps C, Miller D, Salomao D, Wiersema MJ (2001) Impact of EUS-guided fine-needle aspiration on lymph node staging in patients with esophageal carcinoma. Gastrointest Endosc 53(7):751–757. https://doi.org/10.1067/mge.2001.112741

    Article  CAS  PubMed  Google Scholar 

  46. Yoshii T, Ohkawa S, Tamai S, Kameda Y (2013) Clinical outcome of endoscopic mucosal resection for esophageal squamous cell cancer invading muscularis mucosa and submucosal layer. Dis Esophagus 26(5):496–502. https://doi.org/10.1111/j.1442-2050.2012.01370.x

    Article  CAS  PubMed  Google Scholar 

  47. Katada C, Muto M, Momma K, Arima M, Tajiri H, Kanamaru C, Ooyanagi H, Endo H, Michida T, Hasuike N, Oda I, Fujii T, Saito D (2007) Clinical outcome after endoscopic mucosal resection for esophageal squamous cell carcinoma invading the muscularis mucosae—a multicenter retrospective cohort study. Endoscopy 39(9):779–783. https://doi.org/10.1055/s-2007-966761

    Article  CAS  PubMed  Google Scholar 

  48. Teoh AY, Chiu PW, Yu Ngo DK, Wong SK, Lau JY, Ng EK (2010) Outcomes of endoscopic submucosal dissection versus endoscopic mucosal resection in management of superficial squamous esophageal neoplasms outside Japan. J Clin Gastroenterol 44(9):e190–e194. https://doi.org/10.1097/MCG.0b013e3181ce52fb

    Article  PubMed  Google Scholar 

  49. Chiu PW (2006) Endoscopic submucosal dissection-bigger piece, better outcome! Gastrointest Endosc 64(6):884–885. https://doi.org/10.1016/j.gie.2006.06.012

    Article  PubMed  Google Scholar 

  50. Guo HM, Zhang XQ, Chen M, Huang SL, Zou XP (2014) Endoscopic submucosal dissection vs endoscopic mucosal resection for superficial esophageal cancer. World J Gastroenterol 20(18):5540–5547. https://doi.org/10.3748/wjg.v20.i18.5540

    Article  PubMed  PubMed Central  Google Scholar 

  51. Ishihara R, Iishi H, Uedo N, Takeuchi Y, Yamamoto S, Yamada T, Masuda E, Higashino K, Kato M, Narahara H, Tatsuta M (2008) Comparison of EMR and endoscopic submucosal dissection for en bloc resection of early esophageal cancers in Japan. Gastrointest Endosc 68(6):1066–1072. https://doi.org/10.1016/j.gie.2008.03.1114

    Article  PubMed  Google Scholar 

  52. Takahashi H, Arimura Y, Masao H, Okahara S, Tanuma T, Kodaira J, Kagaya H, Shimizu Y, Hokari K, Tsukagoshi H, Shinomura Y, Fujita M (2010) Endoscopic submucosal dissection is superior to conventional endoscopic resection as a curative treatment for early squamous cell carcinoma of the esophagus (with video). Gastrointest Endosc 72(2):255–264, 264 e251–252. https://doi.org/10.1016/j.gie.2010.02.040

    Article  PubMed  Google Scholar 

  53. Pimentel-Nunes P, Dinis-Ribeiro M, Ponchon T, Repici A, Vieth M, De Ceglie A, Amato A, Berr F, Bhandari P, Bialek A, Conio M, Haringsma J, Langner C, Meisner S, Messmann H, Morino M, Neuhaus H, Piessevaux H, Rugge M, Saunders BP, Robaszkiewicz M, Seewald S, Kashin S, Dumonceau JM, Hassan C, Deprez PH (2015) Endoscopic submucosal dissection: European Society of Gastrointestinal Endoscopy (ESGE) Guideline. Endoscopy 47(9):829–854. https://doi.org/10.1055/s-0034-1392882

    Article  PubMed  Google Scholar 

  54. Muguruma N, Okamoto K, Kimura T, Kishi K, Okahisa T, Okamura S, Takayama T (2012) Endoscopic ablation therapy for gastrointestinal superficial neoplasia. Dig Endosc 24(3):139–149. https://doi.org/10.1111/j.1443-1661.2011.01227.x

    Article  PubMed  Google Scholar 

  55. Lal P, Thota PN (2018) Cryotherapy in the management of premalignant and malignant conditions of the esophagus. World J Gastroenterol 24(43):4862–4869. https://doi.org/10.3748/wjg.v24.i43.4862

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  56. Min BH, Kim ER, Lee JH, Kang KJ, Rhee PL, Kim JJ, Rhee JC (2013) Feasibility and efficacy of argon plasma coagulation for early esophageal squamous cell neoplasia. Endoscopy 45(7):575–578. https://doi.org/10.1055/s-0033-1344025

    Article  PubMed  Google Scholar 

  57. Tanaka T, Matono S, Nagano T, Murata K, Sueyoshi S, Yamana H, Shirouzu K, Fujita H (2011) Photodynamic therapy for large superficial squamous cell carcinoma of the esophagus. Gastrointest Endosc 73(1):1–6. https://doi.org/10.1016/j.gie.2010.08.049

    Article  PubMed  Google Scholar 

  58. He S, Bergman J, Zhang Y, Weusten B, Xue L, Qin X, Dou L, Liu Y, Fleischer D, Lu N, Dawsey SM, Wang GQ (2015) Endoscopic radiofrequency ablation for early esophageal squamous cell neoplasia: report of safety and effectiveness from a large prospective trial. Endoscopy 47(5):398–408. https://doi.org/10.1055/s-0034-1391285

    Article  PubMed  PubMed Central  Google Scholar 

  59. Bergman JJ, Zhang YM, He S, Weusten B, Xue L, Fleischer DE, Lu N, Dawsey SM, Wang GQ (2011) Outcomes from a prospective trial of endoscopic radiofrequency ablation of early squamous cell neoplasia of the esophagus. Gastrointest Endosc 74(6):1181–1190. https://doi.org/10.1016/j.gie.2011.05.024

    Article  PubMed  PubMed Central  Google Scholar 

  60. Haidry RJ, Butt MA, Dunn J, Banks M, Gupta A, Smart H, Bhandari P, Smith LA, Willert R, Fullarton G, John M, Di Pietro M, Penman I, Novelli M, Lovat LB (2013) Radiofrequency ablation for early oesophageal squamous neoplasia: outcomes form United Kingdom registry. World J Gastroenterol 19(36):6011–6019. https://doi.org/10.3748/wjg.v19.i36.6011

    Article  PubMed  PubMed Central  Google Scholar 

  61. Jansen M, Scholvinck DW, Kushima R, Sekine S, Weusten BL, Wang GQ, Fleischer DE, Yoshinaga S, Dawsey SM, Meijer SL, Bergman JJ, Oda I (2014) Is it justified to ablate flat-type esophageal squamous cancer? An analysis of endoscopic submucosal dissection specimens of lesions meeting the selection criteria of radiofrequency studies. Gastrointest Endosc 80(6):995–1002. https://doi.org/10.1016/j.gie.2014.09.004

    Article  PubMed  PubMed Central  Google Scholar 

  62. Zhang YM, Boerwinkel DF, Qin X, He S, Xue L, Weusten BL, Dawsey SM, Fleischer DE, Dou LZ, Liu Y, Lu N, Bergman JJ, Wang GQ (2016) A randomized trial comparing multiband mucosectomy and cap-assisted endoscopic resection for endoscopic piecemeal resection of early squamous neoplasia of the esophagus. Endoscopy 48(4):330–338. https://doi.org/10.1055/s-0034-1393358

    Article  PubMed  Google Scholar 

  63. Katada C, Muto M, Manabe T, Boku N, Ohtsu A, Yoshida S (2003) Esophageal stenosis after endoscopic mucosal resection of superficial esophageal lesions. Gastrointest Endosc 57(2):165–169. https://doi.org/10.1067/mge.2003.73

    Article  PubMed  Google Scholar 

  64. Yamamoto H, Kawata H, Sunada K, Sasaki A, Nakazawa K, Miyata T, Sekine Y, Yano T, Satoh K, Ido K, Sugano K (2003) Successful en-bloc resection of large superficial tumors in the stomach and colon using sodium hyaluronate and small-caliber-tip transparent hood. Endoscopy 35(8):690–694. https://doi.org/10.1055/s-2003-41516

    Article  CAS  PubMed  Google Scholar 

  65. Repici A, Hassan C, Carlino A, Pagano N, Zullo A, Rando G, Strangio G, Romeo F, Nicita R, Rosati R, Malesci A (2010) Endoscopic submucosal dissection in patients with early esophageal squamous cell carcinoma: results from a prospective Western series. Gastrointest Endosc 71(4):715–721. https://doi.org/10.1016/j.gie.2009.11.020

    Article  PubMed  Google Scholar 

  66. Kim JS, Kim BW, Shin IS (2014) Efficacy and safety of endoscopic submucosal dissection for superficial squamous esophageal neoplasia: a meta-analysis. Dig Dis Sci 59(8):1862–1869. https://doi.org/10.1007/s10620-014-3098-2

    Article  PubMed  Google Scholar 

  67. Oyama T, Tomori A, Hotta K, Morita S, Kominato K, Tanaka M, Miyata Y (2005) Endoscopic submucosal dissection of early esophageal cancer. Clin Gastroenterol Hepatol 3(7 Suppl 1):S67–S70

    Article  PubMed  Google Scholar 

  68. Fujishiro M, Yahagi N, Kakushima N, Kodashima S, Muraki Y, Ono S, Yamamichi N, Tateishi A, Shimizu Y, Oka M, Ogura K, Kawabe T, Ichinose M, Omata M (2006) Endoscopic submucosal dissection of esophageal squamous cell neoplasms. Clin Gastroenterol Hepatol 4(6):688–694. https://doi.org/10.1016/j.cgh.2006.03.024

    Article  PubMed  Google Scholar 

  69. Committee AT, Maple JT, Abu Dayyeh BK, Chauhan SS, Hwang JH, Komanduri S, Manfredi M, Konda V, Murad FM, Siddiqui UD, Banerjee S (2015) Endoscopic submucosal dissection. Gastrointest Endosc 81(6):1311–1325. https://doi.org/10.1016/j.gie.2014.12.010

    Article  Google Scholar 

  70. Suzuki S, Gotoda T, Kobayashi Y, Kono S, Iwatsuka K, Yagi-Kuwata N, Kusano C, Fukuzawa M, Moriyasu F (2016) Usefulness of a traction method using dental floss and a hemoclip for gastric endoscopic submucosal dissection: a propensity score matching analysis (with videos). Gastrointest Endosc 83(2):337–346. https://doi.org/10.1016/j.gie.2015.07.014

    Article  PubMed  Google Scholar 

  71. Takezawa T, Hayashi Y, Shinozaki S, Sagara Y, Okada M, Kobayashi Y, Sakamoto H, Miura Y, Sunada K, Lefor AK, Yamamoto H (2019) The pocket-creation method facilitates colonic endoscopic submucosal dissection (with video). Gastrointest Endosc 89(5):1045–1053. https://doi.org/10.1016/j.gie.2019.01.022

    Article  PubMed  Google Scholar 

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Zhang, R., Lau, L.H.S., Wu, P.I.C., Yip, HC., Wong, S.H. (2020). Endoscopic Diagnosis and Treatment of Esophageal Squamous Cell Carcinoma. In: Lam, A. (eds) Esophageal Squamous Cell Carcinoma. Methods in Molecular Biology, vol 2129. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-0377-2_5

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  • DOI: https://doi.org/10.1007/978-1-0716-0377-2_5

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  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-0376-5

  • Online ISBN: 978-1-0716-0377-2

  • eBook Packages: Springer Protocols

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