Abstract
Chest pain is generally interpreted as a symptom of cardiac dysfunction, usually myocardial ischemia, but the relationship of chest pain and ischemia is weak. Psychological states and traits (notably anxiety and depression) are strongly associated with chest pain in patients with known coronary artery disease both when measurable ischemia occurs and when ischemia cannot be concomitantly detected. Intense emotional arousal (anger and panic) is a known precipitant of symptomatic and asymptomatic (“silent”) ischemia. In addition to ischemia-related chest pain, noncardiac chest pain is a common medical problem that is also associated with anxiety and depression. Treatment of emotional distress has been found to help diminish chest pain in both patients with cardiac and noncardiac chest pain and reduce ischemia in patients with coronary artery disease.
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References
Allison TG, Williams DE, Miller TD, Patten CA, Bailey KR, Squires RW, Gau GT (1995) Medical and economic costs of psychologic distress in patients with coronary artery disease. Mayo Clin Proc 70:734–742
Amorosa-Tupler B, Tapp JT, Cardia RV (1989) Stress management through relaxation and imagery in the treatment of angina pectoris. J Cardpulm Rehabil 9:348–355
Ballenger JC (1987) Unrecognized prevalence of panic disorder in primary care, internal medicine and cardiology. Am J Cardiol 60:39J–47J
Barloon TJ, Noyes R (1997) Charles Darwin and panic disorder. JAMA 277(2):138–141
Barry J, Selwyn AP, Nabel EG, Rocco MB, Campbell S, Rebecca G (1988) Frequency of st-segment depression produced by mental stress in stable angina pectoris from coronary artery disease. Am J Cardiol 61:989–993
Barsky AJ, Hochstrasser B, Coles A, Zisfein J, O’Donnell C, Eagle K (1990) Silent myocardial ischemia: is the person or the event silent? JAMA 264:1132–1135
Beitman BD, Kushner MG, Basha I, Lamberti J, Mukerji V, Barthels K (1991a) Followup status of patients with angiographically normal coronary arteries and panic disorder. JAMA 265(12):1545–1549
Beitman BD, Kushner M, Grossberg GT (1991b) Late onset panic disorder: evidence from a study of patients with chest pain and normal cardiac evaluations. Int J Psychiatry Med 21(1):29–35
Beitman BD, Mukerji V, Russell JL, Grafing M (1993) Panic disorder in cardiology patients: a review of the Missouri panic/cardiology project. J Psychiatr Res 27(1):35–46
Bengston A, Herliz J, Karlsson T, Hjalmarson A (1996) Distress correlates with the degree of chest pain: a description of patients awaiting revascularization. Heart 75:257–260
Bienenfeld L, Frishman W, Glasser SP (1996) The placebo effect in cardiovascular disease. Am Heart J 132:1207–1221
Black JL, Allison TG, Williams DE, Rummans TA, Gau GT (1998) Effect of intervention for psychological distress on rehospitalization rates in cardiac rehabilitation patients. Psychosomatics 39:134–143
Blumenthal JA, Jiang W, Babyak MA, Krantz DS, Frid DJ, Coleman RE, Waugh R, Hanson M, Appelbaum M, O’Connor C, Morris JJ (1997) Stress management and exercise training in cardiac patients with myocardial ischemia. Arch Intern Med 157:2213–2223
Blumenthal JA, Babyak M, Wei J, O’Connor C, Waugh R, Eisenstein E, Mark D, Sherwood A, Woodley PS, Irwin RJ, Reed G (2002) Usefulness of psychosocial treatment of mental stress induced myocardial ischemia in men. Am J Cardiol 89:164–168
Boden WE, et al., for the COURAGE Trial Research Group (2007) Optimal medical therapy with or without PCI for stable coronary disease. N Engl J Med 356:1503–1516
Boltwood MD, Taylor CB, Burke MB, Grogin H, Giacomini J (1993) Anger report predicts coronary artery vasomotor response to mental stress in atherosclerotic segments. Am J Cardiol 72:1361–1365
Bringager CB, Dammen T, Friis S (2004) Nonfearful panic disorder in chest pain patients. Psychosomatics 45:69–79
Buffon A, Biasucci LM, Liuzzo G, D’Onofrio G, Crea F, Maseri A (2002) Widespread coronary inflammation in unstable angina. N Engl J Med 347:5–12
Burell G (1996) Group psychotherapy in project new life: treatment of coronary-prone behaviors for patients who have had coronary artery bypass graft surgery. In: Allan R, Scheidt S (eds) Heart & mind: the practice of cardiac psychology. American Psychological Association, Washington, DC, pp 291–312
Cannon RO, Camici PG, Epstein SE (1992) Pathophysiological dilemma of syndrome X. Circulation 85:883–892
Cannon RO, Quyyumi AA, Mincemoyer MA, Stine AM, Gracely RH, Smith WB, Geraci MF, Black BC, Uhde TW, Waclawiw MA et al (1994) Imipramine in patients with chest pain despite normal coronary angiograms. N Engl J Med 330:1411–1417
Carney RM, Freedland KE, Ludbrook PA, Saunders RD, Jaffe AS (1990) Major depression, panic disorder and mitral valve prolapse in patients who complain of chest pain. Am J Med 89:757–760
Cobb LA, Thomas GI, Dillard DH et al (1959) An evaluation of internal-mammary-artery ligation by a double-blind technic. N Engl J Med 260:1115–1118
Contrada, R. J., Lacy, C. R., Robbins, M. L. et al. (1990). Mental stress reduces coronary artery diameter. Proceedings of the 11th Annual Meeting of the SBM #125:D08.
Cooke RA, Anggiansah A, Wang J, Chambers JB, Owen W (1996) Hyperventilation and esophageal dysmotility in patients with noncardiac chest pain. Am J Gastroenterol 91(3):480–484
Costa PT, Zonderman AB, Engel BT, Baile WF, Brimlow DL, Brinker J (1985) The relation of chest pain symptoms to angiographic findings of coronary artery stenosis and neuroticism. Psychosom Med 47:285–293
Davidson KW (2000) Dose-response relations between hostility reductions and cardiac related hospitalizations. Psychosom Med 62:149
Davies RF, Linden W, Habibi H, Klinke WP, Nadeau C, Phaneuf DC, Lepage S, Dessain P, Buttars JA (1993) Relative importance of psychologic traits and severity of ischemia in causing angina during treadmill exercise. J Am Coll Cardiol 21:331–336
Deanfield JE, Shea M, Kensett M, Horlock P, Wilson RA, de Lansheere CM, Selwyn AP (1984) Silent myocardial ischemia due to mental stress. Lancet 2:1001–1005
DeCosta JM (1871) On irritable heart: a functional form of cardiac disorder and its consequences. Am J Sci 61:14–51
Depre C, Wijns W, Robert AM, Renkin JP, Havaux X (1997) Pathology of unstable plaque: correlation with the clinical severity of acute coronary syndromes. J Am Coll Cardiol 30:694–702
Dimond EG, Kittle CF, Crockett JE (1960) Comparison of internal-mammary artery ligation and sham operation for angina pectoris. Am J Cardiol 4:483–486
Epstein SE, Gerber LH, Borer JS (1979) Chest wall syndrome: a common cause of unexplained chest pain. JAMA 241:2793–2797
Fleet R, Lesperance F, Arsenault A, Gregoire J, Lavoie K, Laurin C, Harel F, Burelle D, Lambert J, Beitman B, Frasure-Smith N (2005) Myocardial perfusion study of panic attacks in patients with coronary artery disease. Am J Cardiol 96:1064–1068
Fox M, Forgacs I (2006) Unexplained (non-cardiac) chest pain. Clin Med 6(5):445–449
Frasure-Smith N, Lesperance F (1998) Depression and anxiety increase physician costs during the first post-MI year. Psychosom Med 60:99
Friedman M, Thoreson CE, Gill JJ et al (1986) Alteration of type a behavior and its effect on recurrences in post-myocardial infarction patients: summary results of the recurrent coronary prevention project. Am Heart J 112:653–665
Friedman M, Powell LH, Thoreson CE et al (1987) Effect of discontinuance of type a behavioral counseling on type a behavior and cardiac recurrence rate in post-myocardial infarction patients. Am Heart J 114:483–489
Friedman M, Breall WS, Goodwin ML, Sparagon BJ, Ghandour G, Fleischman N (1996) Effect of type a behavioral counseling on frequency of episodes of silent myocardial ischemia in coronary patients. Am Heart J 132:933–937
Gallacher JEJ, Hopkinson CA, Bennett P, Burr ML, Elwood PC (1997) Effect of stress management on angina. Psychol Health 12:523–532
Gardner WN, Bass C (1989) Hyperventilation in clinical practice. Br J Hosp Med 41:73–81
Gold H, Kwit NT, Otto H (1937) The xanthines (theobromine and aminophylline) in the treatment of cardiac pain. JAMA 108:2173–2179
Gulliksson M, Burell G, Vessby B, Lundin L, Toss H, Svardsudd K (2011) Randomized controlled trial of cognitive behavioral therapy vs standard treatment to prevent recurrent cardiovascular events in patients with coronary heart disease: Secondary Prevention in Uppsala Primary Health Care Project (SUPRIM). Arch Intern Med 171(2):134–140
Heberden W (1772) Some account of a disorder of the breast. Med Trans Coll Phys 2:59–67
Hick DG, Morrison JFB, Casey JF (1992) Oesophageal motility, luminal pH and electrocardiographic ST-segment analysis during spontaneous episodes of angina like chest pain. Gut 33:79–86
Hollander JE (1995) The management of cocaine-associated myocardial ischemia. N Engl J Med 333:1267–1272
Howell JD (1985) “Soldier’s Heart”: the redefinition of heart disease and specialty formation in early twentieth century Great Britain. Med Hist 5:34–52
Huffman JC, Smith FA, Blais MA, Jannuzzi JL, Fricchione GL (2008) Anxiety independent of depressive symptoms, is associated with in-hospital complications after acute myocardial infarction. J Psychosom Res 65:557–563
Ioannidis JPA (2005) Contradicted and initially stronger effects in highly cited clinical research. JAMA 294:218–228
Janne P et al (1988) The spouse as a possible angina warning system in silent myocardial ischemia. Eur Heart J 9N:21–24
Jenkins CD, Stanton B-A, Klein MD, Savageau JA, Harken DE (1983) Correlates of angina pectoris among men awaiting coronary bypass surgery. Psychosom Med 45:141–153
Jiang W, Velazquez EJ, Kuchibhatla M, Samad Z, Boyle SH, Kuhn C, Becker RC, Ortel TL, Williams RB, Rogers JG, O’Connor C (2013) Effect of escitalopram on mental stress-induced myocardial ischemia: results of the REMIT trial. JAMA 309(20):2139–2149
Johnston DW, Lo CR (1983) The effects of cardiovascular feedback and relaxation on angina pectoris. Behav Psychother 11:257–264
Kamarck TW, Haskett RF, Muldoon M, Flory JD, Anderson B, Bies R, Pollack B, Manuck SB (2009) Citalopram intervention for hostility: results of a randomized clinical trial. J Consult Clin Psychol 77(1):174–188
Katon W, Hall ML, Russo J (1988) Chest pain: relationship of psychiatric illness to coronary angiographic results. Am J Med 84:1–9
Katritsis D et al (2007) Update of meta-analysis of pci, as compared with medical treatment, for stable coronary artery disease. N Engl J Med 57:414–418
Kenyon LW, Ketterer MW, Gheorgiade M, Goldstein S (1991) Psychological factors related to prehospital delay during acute myocardial infarction. Circulation 84(5):1969–1976
Ketterer MW (1985) Awareness I: the natural ecology of subjective experience and the mind-brain problem revisited. JMB 6(4):469–513
Ketterer MW (1992) Denial specific to Friedman’s pathogenic emotions in Jenkins activity survey type a and angiography-referred males. Psychosomatics 33(1):72–80
Ketterer MW, Kenyon L, Foley BA, Brymer J, Rhoads K, Kraft P, Lovallo WR (1996a) Denial of depression as an independent correlate of coronary artery disease. J Health Psychol 1:93–105
Ketterer MW, Brymer J, Rhoads K, Kraft P, Kenyon L, Lovallo WR, Voight CJ (1996b) Emotional distress among males with “syndrome x”. J Behav Med 19(5):455–465
Ketterer MW, Huffman J, Lumley MA, Wassef S, Gray L, Kenyon L, Kraft P, Brymer J, Rhoads K, Lovallo WR, Goldberg AD (1998) Five year follow up for adverse outcomes in males with at least minimally positive angiograms: the importance of “denial” in assessing psychosocial risk factors. J Psychosom Res 44(2):241–250
Ketterer MW, Fitzgerald F, Keteyian SJ, Thayer B, Jordan M, McGowan C, Mahr G, Manganas A, Goldberg AD (2000a) Chest pain and the treatment of psychosocial / emotional distress in cad patients. J Behav Med 23:437–450
Ketterer MW, Freedland KE, Krantz DS, Kaufmann P, Forman S, Greene A, Raczynski J, Knatterud G, Light K, Carney RM, Stone P, Becker L, Sheps D, for the PIMI Investigators. (2000b) Psychological correlates of mental stress induced ischemia in the laboratory: the Psychophysiological Investigation of Myocardial Ischemia (PIMI) study. J Health Psychol 5(1):75–85
Ketterer MW, Mahr G, Goldberg AD (2000c) Psychological factors affecting a medical condition: ischemic coronary heart disease. J Psychosom Res 48(4/5):357–368
Ketterer MW, Denollet J, Goldberg AD, McCullough PA, John S, Farha AJ, Clark V, Keteyian S, Chapp J, Thayer B, Deveshwar S (2002) The big mush: psychometric measures are confounded and nonindependent in their association with age at initial diagnosis of ICHD. J Cardiovasc Risk 9(1):41–48
Ketterer MW, Mahr G, Cao JJ, Hudson M, Smith S, Knysz W (2004a) What’s “unstable” in unstable angina? Psychosomatics 45(3):185–196
Ketterer MW, Denollet J, Chapp J, Thayer B, Keteyian S, Clark V, John S, Farha AJ, Deveshwar S (2004b) Men deny and women cry, but who dies? Do the wages of “denial” include early ischemic heart disease? J Psychosom Res 56:119–123.f
Ketterer MW, Knysz W, Keteyian SJ, Khanal S, Schairer J, Jafri S, Alam M, Farha AJ (2008) Cardiovascular symptoms in coronary artery disease patients are strongly correlated with emotional distress. Psychosomatics 49:230–234
Ketterer MW, Knysz W, Khandelwal A, Keteyian SJ, Farha AJ, Deveshwar S (2010) Healthcare utilization and emotional distress in cad patients. Psychosomatics 51(4):297–301
Ketterer MW, Bekkouche NS, Goldberg AD, McMahon RP, Krantz DS (2011) Symptoms of anxiety & depression are correlates of angina pectoris by recent history & on an ischemia positive treadmill test in patients with documented coronary artery disease in the PIMI study. Cardiovasc Psychiatry Neurol 1–7:www.hindawi.com/journals/cpn
Kisely S, Campbell LA, Skerritt P (2008) Psychological interventions for symptomatic management of non-specific chest pain patients with normal coronary anatomy. Cochrane Database Syst Rev 4. www.cochrane.org/reviews/
Kloner RA, Hale S, Alker K, Rezkalla S (1992) The effects of acute and chronic cocaine use on the heart. Circulation 85:407–419
Kneip RC, Delamater AM, Ismond T, Milford C, Salvia L, Schwartz D (1993) Self and spouse ratings of anger and hostility as predictors of coronary heart disease. Health Psychol 12:301–302
Krantz DS, Hedges SM, Gabbay FH et al (1994) Triggers of angina and ST- segment depression in ambulatory patients with coronary artery disease: evidence for an uncoupling of angina and ischemia. Am Heart J 128:703–712
Kushner MG, Beitman BD, Beck NC (1989) Factors predictive of panic disorder in cardiology patients with chest pain and no evidence of coronary artery disease: a cross-validation. J Psychosom Res 33(2):207–215
Kushner MG, Thomas AM, Bartels KM, Beitman BD (1992) Panic disorder history in the families of patients with angiographically normal coronary arteries. Am J Psychiatry 149:1563–1567
Ladwig KH, Roll G, Breithardt G, Borggrefe C (1999) Extracardiac contributions to chest pain perception in patients 6 months after acute myocardial infarction. Am Heart J 137:528–535
Lewin B, Robertson IH, Cay EL, Irving JB, Campbell M (1992) Effects of self-help post-myocardial infarction rehabilitation on psychological adjustment and use of health services. Lancet 339:1036–1040
Lewin RJP, Cay EL, Todd I, Soryal I, Goodfield N, Bloomfield P, Elton R (1995) The angina management programme: a rehabilitation treatment. BJC 1:221–226
Light KC, Herbst MC, Bragdon EE et al (1991) Depression and type a behavior pattern in patients with coronary artery disease: relationship to painful versus silent myocardial ischemia and beta-endorphin responses during exercise. Psychosom Med 53:669–683
Linden W, Davies RF, Dessain P, Habibi H, Klinke WP, Buttars J, the CASIS Investigators. (1991) Consistent under-reporting of physical and psychological symptoms in a subgroup of silent ischemia patients. Psychosom Med 53:216–217
Lumley MA, Torosian T, Ketterer MW, Pickard SD (1997a) Psychosocial factors related to noncardiac chest pain during treadmill exercise. Psychosomatics 38:230–238
Lumley MA, Tomakowsky J, Torosian T (1997b) The relationship of alexithymia to subjective and biomedical measures of disease. Psychosomatics 38:497–502
Lumley MA, Torosian T, Rowland LL, Ketterer MW, Pickard SD (1997c) Correlates of unrecognized acute myocardial infarction detected via perfusion imaging. Am J Cardiol 79:1170–1173
Lumley MA, Rowland L, Torosian T, Bank A, Ketterer MW, Pickard SD (2000) Decreased health care use among patients with silent myocardial ischemia; support for a generalized rather than cardiac-specific silence. J Psychosom Res 48:479–484
Margraf J, Ehlers A, Roth WT (1988) Mitral valve prolapse and panic disorder: a review of their relationship. Psychosom Med 50:93–113
Markovitz JH (1998) Hostility is associated with increased platelet activation in coronary heart disease. Psychosom Med 60:586–591
McCroskery JH, Malloy TE, Lantinga LJ, Sprafkin RP, Warner RA, Hill NE (1991) Mitral valve prolapse and neuroticism in chest pain patients with normal and diseased coronary arteries. Int J Psychiatry Med 21(3):233–244
Miller PF, Light KC, Bragdon EE et al (1993) Beta-endorphin responses to exercise and mental stress in patients with ischemic heart disease. J Psychosom Res 37:455–465
Mueller RL, Rosengart TK, Isom OW (1997) The history of surgery for ischemic heart disease. Ann Thorac Surg 63:869–878
Mukerji V, Beitman BD, Lamberti JW, DeRosear L, Basha I, Alpert MA (1987) Prevalence of panic attacks and panic disorder in patients with chest pain and normal coronary arteries. Psychosom Med 49(2):206
Mumford E, Schlesinger LW, Glass GV (1982) The effect of psychological intervention on recovery from surgery and heart attacks: an analysis of the literature. Am J Public Health 72(2):141–151
Nejad SH, Alpay M (2010) Pain patients. In: Stern TA, Fricchione GL, Cassem NH, Jellinek MS, Rosenbaum JF (eds) Massachusetts General Hospital handbook of general hospital psychiatry. Saunders/Elsevier, Philadelphia
Nesto RW, Waxman S, Mittleman MA, Sassover MA, Fitzpatrick PJ, Lewis SM, Leeman DE, Subrooks SJ, Manzo K, Zarich SW (1998) Angioscopy of culprit coronary lesions in unstable angina pectoris and correlation of clinical presentation with plaque morphology. Am J Cardiol 81:225–228
Ohman EM, Alexander KP (2014) The challenges with chronic angina. N Engl J Med 371(12):1152–1153
Payne TJ, Johnson CA, Penzien DB, Poirzelius J, Eldridge G, Parisi S, Beckham J, Pbert L, Prather R, Rodriguez G (1994) Chest pain self management training for patients with coronary artery disease. J Psychosom Res 38:409–418
Petrie KJ, Cameron LD, Ellis CJ, Buick D, Weinman J (2002) Changing illness perceptions after myocardial infarction: an early intervention randomized trial. Psychosom Med 64:580–586
Qureshi AI, Suri FK, Guterman LR, Hopkins LN (2001) Cocaine use and the likelihood of nonfatal myocardial infarction and stroke: data from the third national health and nutrition examination survey. Circulation 103:502–506
Ramsay J, McDermott MR, Bray C (2001) Components of the anger-hostility complex and symptom reporting in patients with coronary artery disease: a multi-measure study. J Health Psychol 6:713–729
Rasheed Q, Nair RN, Sheehan HM, Hodgson JM (1995) Coronary artery plaque morphology in stable angina and subsets of unstable angina: an in vivo intracoronary ultrasound study. Int J Card Imaging 11:89–95
Richter JE (1992) Overview of diagnostic testing for chest pain of unknown origin. Am J Med 92(5A):41s–45s
Rounsaville BJ, Anton SF, Carroll K, Budde D, Prusoff BA, Gawain F (1991) Psychiatric diagnoses of treatment-seeking cocaine abusers. Arch Gen Psychiatry 48:45–52
Shelby RA, Somers TJ, Keefe FJ, Silva SG, McKeee DC, She L, Waters SJ, Varia I, Riordan YB, Knowles VM, Blazing M, Blumenthal JA, Johnson P (2009) Pain catastrophizing in patients with noncardiac chest pain: relationships with pain, anxiety and disability. Psychosom Med 71:861–868
Siegman AW, Townsend ST, Blumenthal RS, Sorkin JD, Civelek AC (1998) Dimensions of anger and CHD in men and women: self-ratings versus spouse ratings. J Behav Med 21:315–336
Smith TW, Follick MJ, Korr KS (1984) Anger, neuroticism, type a behavior and the experience of angina. BJMP 57:249–252
Smith TW, Uchino BN, Berg CA, Florsheim P, Pearce G, Hawkins M, Henry NJM, Beveridge RM, Skinner MA, Hopkins PN (2008) Associations of self-reports versus spouse ratings of negative affectivity, dominance and affiliation with coronary artery disease: where should we look and who should we ask when studying personality and health? Health Psychol 27(6):676–684
Strike PC, Magid K, Brydon L et al (2004) Exaggerated platelet and hemodynamic reactivity to mental stress in men with coronary artery disease. Psychosom Med 66:492–500
Suls J, Bunde J (2005) Anger, anxiety and depression as risk factors for cardiovascular: the problems and implications of overlapping affective dispositions. Psychol Bull 131(2):260–300
Thompson D, Hylan TR, McMullen W et al (1998) Predictors of medical offset effect among patients receiving antidepressant therapy. Am J Psychiatry 155:824–827
Topol EJ, Nissen SE (1995) Our preoccupation with coronary luminology: the dissociation between clinical and angiographic findings in ischemic heart disease. Circulation 92:2333–2342
Torosian T, Lumley MA, Pickard SD, Ketterer MW (1997) Silent versus symptomatic myocardial ischemia: the role of psychological and medical factors. Health Psychol 16(2):123–130
Verthein U, Kohler T (1997) The correlation between everyday stress and angina pectoris: a longitudinal study. J Psychosom Res 43:241–245
Vitaliano PP, Katon W, Maiuro RD, Russo J (1989) Coping in chest pain patients with and without psychiatric disorders. J Consult Clin Psychol 57(3):338–343
Weber JE, Shofer FS, Larkin L, Kalaria AS, Hollander JE (2003) Validation of a brief observation period for patients with cocaine-associated chest pain. N Engl J Med 348:510–517
Weintraub WS et al for the COURAGE Trial Research Group (2008) Effect of PCI on quality of life in patients with stable coronary disease. N Engl J Med 359(7):677–687
Wielgosz AT, Earp J (1986) Perceived vulnerability to serious heart disease and persistent pain in patients with minimal or no coronary disease. Psychosom Med 48(1/2):118–124
Wittstein IS, Thiemann DR, Lima JA et al (2005) Neurohumoral features of myocardial stunning due to sudden emotional stress. N Engl J Med 352(6):539–548
Wooley CF (1985) From irritable heart to mitral valve prolapse: British army medical reports, 1860–1870. Am J Cardiol 55:1107–1109
Wooley CF (1987) From irritable heart to mitral valve prolapse: World War I – the U.S. experience and the origin of neurocirculatory asthenia. Am J Cardiol 59:1183–1186
Wulsin LR, Arnold LM, Hillard JR (1991) Axis I disorder in ER patients with atypical chest pain. Int J Psychiatry Med 21(1):37–46
Yeung AC, Vekschtein VI, Krantz DS, Vita JA, Ryan TJ, Ganz P, Selwyn AP (1991) The effect of atherosclerosis on the vasomotor response of coronary arteries to mental stress. N Engl J Med 325:1551–1556
Zhang Z-M, Rautaharju PM, Prineas RJ, Rodriguez CJ, Loehr L, Rosamond WD, Kitzan D, Cooper D, Solimon EZ (2014) Race and sex differences in the incidence and prognostic significance of silent myocardial infarction in the Atherosclerotic Risk in Communities (ARIC) study. Circulation 133(22):2141–2148
Zvolensky MJ, Feidner MT, Eifert GH, Vujanovic AA, Solomon SE (2008) Cardiophobia: a critical analysis. Trans Psychiatr 45:230–252
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Ketterer, M.W., Lumley, M.A., Schairer, J., Farha, A., Knysz, W. (2022). Chest Pain: Cardiac and Non-Cardiac. In: Waldstein, S.R., Kop, W.J., Suarez, E.C., Lovallo, W.R., Katzel, L.I. (eds) Handbook of Cardiovascular Behavioral Medicine. Springer, New York, NY. https://doi.org/10.1007/978-0-387-85960-6_45
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