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Keloids

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Abstract

Keloidal scarring has been described by many cultures dating back as far as the Smith Papyrus in 3000 bc. The Yoruba tribe of Western Africa gives us perhaps the most complete record of ancient knowledge with their painting and sculpture of keloids circa 1600 ad. Despite this long history of knowledge and the explosion of medical care in other arenas, we have made minimal progress since the Yorubas toward understanding keloid prevention and eradication. No small measure of our current lack of consistently reliable, safe treatment measures is grounded in our ignorance of keloid pathogenesis. Prevention, too, is hampered by aspects of keloid occurrence that are out of our control. One can avoid trauma resulting from voluntary and elective procedures to adorn, augment, or improve. Aggressive prevention of keloids after accidental trauma and necessary surgery is also potentially within our abilities. However, most aspects of keloid formation are out of our control: ethnicity, skin pigmentation, age, gender, and genetic makeup. This chapter will briefly review what is known about keloid epidemiology and pathogenesis in an effort to gain insight into the development of a rational treatment and prevention plan for these unsightly lesions.

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  1. State University of New York, 450 Clarkson Avenue, 46, Brooklyn, NY, 11203, USA

    Hilary Baldwin M.D.

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  1. Department of Dermatology, St. Luke’s Roosevelt Hospital, Skin of Color Center, New York, 10025, New York, USA

    Andrew F. Alexis

  2. Rush University, Department of Dermatology, Chicago, 60602, Illinois, USA

    Victoria H. Barbosa

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Baldwin, H. (2013). Keloids. In: Alexis, A., Barbosa, V. (eds) Skin of Color. Springer, New York, NY. https://doi.org/10.1007/978-0-387-84929-4_10

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