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Bidirectional Relations Among Depression, Migraine, and Epilepsy: Do They Have an Impact on Their Response to Treatment?

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Psychiatric and Behavioral Aspects of Epilepsy

Part of the book series: Current Topics in Behavioral Neurosciences ((CTBN,volume 55))

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Abstract

The evaluation and treatment of patients with epilepsy is not limited to the type of epilepsy, but it must incorporate the common comorbid neurologic, psychiatric, and medical disorders, as the latter can bare an impact on the course and response to treatment of the seizure disorder and vice versa. In this article we review the bidirectional relations among epilepsy and two of its most common comorbidities, mood disorders and migraine and examine the implications of these relations on the selection of therapies of these three disorders and their response to treatment. We also review the most salient common pathogenic mechanisms that may explain such relations.

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Authors and Affiliations

  1. Comprehensive Epilepsy Center and Epilepsy Division, Department of Neurology, University of Miami, Miller School of Medicine, Miami, FL, USA

    Andres M. Kanner

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  1. Department of Neuroscience Central Clinical School, Monash University, Melbourne, Australia

    Nigel C. Jones

  2. Miller School of Medicine, University of Miami, Miami, FL, USA

    Andres M. Kanner

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Kanner, A.M. (2021). Bidirectional Relations Among Depression, Migraine, and Epilepsy: Do They Have an Impact on Their Response to Treatment?. In: Jones, N.C., Kanner, A.M. (eds) Psychiatric and Behavioral Aspects of Epilepsy . Current Topics in Behavioral Neurosciences, vol 55. Springer, Cham. https://doi.org/10.1007/7854_2021_286

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