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Clinical Outcome in Patients with Nosocomial COVID-19 Infection After Thoracic Surgery

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Invasive Diagnostics and Therapy

Abstract

In the present study, we retrospectively evaluated outcomes in 8 patients (mean age 67 ± 7, range 55–77 years; male/female 7/1) who acquired nosocomial COVID-19 infection postoperatively out of the 39 adults who underwent elective thoracic surgery in November 2020. All patients were tested negative for COVID-19 on admission. The mortality rate in the eight patients was 25%. The surviving six patients were discharged in a good clinical condition. Fatal outcomes were due to the development of severe and unrelenting acute respiratory distress syndrome (ARDS) and were associated with preoperatively reduced serum albumin (<3 g/dL), an open surgical approach, oxygen saturation <90% at the time of COVID-19 diagnosis, and the real-time PCR cycle threshold (Ct) value <20. A high mortality rate indicates a need for systematic and frequent COVID-19 screening in patients scheduled for elective thoracic surgery and the use of minimally invasive procedures whenever feasible.

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Conflicts of Interest

The authors declare no conflicts of interest concerning this study.

Ethical Approval

This article based on a retrospective review of anonymized medical files does not contain any direct studies with human participants performed by any of the authors. Thus, the requirements for patient consent and the institutional Ethics Committee approval were waived.

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Correspondence to Volkan Kösek .

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Al Masri, E. et al. (2021). Clinical Outcome in Patients with Nosocomial COVID-19 Infection After Thoracic Surgery. In: Pokorski, M. (eds) Invasive Diagnostics and Therapy. Advances in Experimental Medicine and Biology(), vol 1374. Springer, Cham. https://doi.org/10.1007/5584_2021_667

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