Abstract
Psychological factors, such as the anxiety and depression, which often occur in patients with lung cancer might negatively influence their quality of life. The aim of the study was to evaluate the effect of anxiety and depression in lung cancer patients on quality of life. The study included 180 lung patients of the mean age of 62.7 ± 9.7 years. The following scales were employed in the study: Quality of Life Questionnaire QLQ-C30 and LC13 scale, and Hospital Anxiety and Depression scale (HADS). The overall score of quality of life measured by QLQ-C30 was 47.1 ± 23.4 points on a hundred-point scale. Anxiety was diagnosed in 67 patients (37.2%) and depression in 75 patients (41.7%) by HADS. Quality of life was significantly worse in case of anxiety and depression (p < 0.05), which negatively influenced both functional and symptom intensity scales measured with QLQ-C30 and QLQ-LC13. We conclude that early identification of anxiety and depression may help in therapeutic decision-making and may be a useful predictive factor in lung cancer patients.
This is a preview of subscription content, log in via an institution to check access.
References
Arrieta O, Angulo LP, Núñez-Valencia C, Dorantes-Gallareta Y, Macedo EO, Martinez-Lopez D, Alvarado S, Corona-Cruz JF, Onate-Ocana LF (2013) Association of depression and anxiety on quality of life, treatment adherence, and prognosis in patients with advanced non-small cell lung cancer. Ann Surg Oncol 20(6):1941–1948
Bergman B, Aaronson NK, Ahmezdai S, Kaasa S, Sullivan M (1994) The EORTC QLQ-LC13: a modular supplement to the EORTC core quality of life questionnaire (QLQ-C30) for use in lung cancer clinical trials. Eur J Cancer 30:635–642
Bjelland I, Dahl AA, Haug TT, Neckelmann D (2002) The validity of the hospital anxiety and depression scale. An updated literature review. J Psychosom Res 52(2):69–77
Carlsen K, Jensen AB, Jacobsen E, Krasnik M, Johansen C (2005) Psychosocial aspects of lung cancer. Lung Cancer 47(3):293–300
Hopwood P, Stephens RJ (2000) Depression in patients with lung cancer: prevalence and risk factors derived from quality-of-life data. J Clin Oncol 18(4):893–903
Iyer S, Taylor-Stokes G, Roughley A (2013) Symptom burden and quality of life in advanced non-small cell lung cancer patients in France and Germany. Lung Cancer 81(2):288–293
Li TC, Li CI, Tseng CH, Lin KS, Yang SY, Chen CY, Hsia TC, Lee YD, Lin CC (2012) Quality of life predicts survival in patients with non-small cell lung cancer. BMC Public Health 12:790
Liao YC, Shun SC, Liao WY, Yu CJ, Yang PC, Lai YH (2014) Quality of life and related factors in patients with newly diagnosed advanced lung cancer: a longitudinal study. Oncol Nurs Forum 41(2):E44–E55
Mor V, Allen S, Malin M (1994) The psychosocial impact of cancer on older versus younger patients and their families. Cancer 74(7Suppl):2118–2127
Pirl WF, Greer JA, Traeger L, Jackson V, Lennes IT, Gallagher ER, Perez-Cruz P, Heist RS, Temel JS (2012) Depression and survival in metastatic non-small-cell lung cancer: effects of early palliative care. J Clin Oncol 30(12):1310–1315
Polanski J, Jankowska-Polanska B, Rosinczuk J, Chabowski M, Szymanska-Chabowska A (2016) Quality of life of patients with lung cancer. Onco Targets Ther 9:1023–1028
Pula B, Werynska B, Olbromski M, Muszczynska-Bernhard B, Chabowski M, Janczak D, Zabel M, Podhorska-Okolow M, Dziegiel P (2014) Expression of Nogo isoforms and Nogo-B receptors (NgBR) in non-small cell lung carcinomas. Anticancer Res 34(8):4059–4068
Trzebiatowska I (2000) Anxiety disturbances in the cancer disease – practical aspect. Psychoonkologia 6:49–53. (Article in Polish)
Zabora J, BrintzenhofeSzoc K, Curbow B, Hooker C, Piantadosi S (2001) The prevalence of psychological distress by cancer site. Psychooncology 10(1):19–28
Zigmond AS, Snaith RP (1983) The hospital anxiety and depression scale. Acta Psychiatr Scand 67(6):361–370
Zimmermann C, Burman D, Swami N, Krzyzanowska MK, Leighl N, Moore M, Rodin G, Tannock I (2011) Determinants of quality of life in patients with advanced cancer. Support Care Cancer 19(5):621–629
Conflicts of Interest
The authors declare no conflicts of interest in relation to this article.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2017 Springer International Publishing Switzerland
About this chapter
Cite this chapter
Polański, J. et al. (2017). Intensity of Anxiety and Depression in Patients with Lung Cancer in Relation to Quality of Life. In: Pokorski, M. (eds) Pulmonary Disorders and Therapy. Advances in Experimental Medicine and Biology(), vol 1023. Springer, Cham. https://doi.org/10.1007/5584_2017_50
Download citation
DOI: https://doi.org/10.1007/5584_2017_50
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-73702-7
Online ISBN: 978-3-319-73703-4
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)