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Introduction to the Special Issue on Purinergic Receptors

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Protein Reviews

Part of the book series: Advances in Experimental Medicine and Biology ((PROTRE,volume 1051))

Abstract

In this Introduction to the series of papers that follow about purinergic receptors, there is a brief history of the discovery of purinergic signalling, the identity of purinoceptors and the current recognition of P1, P2X and P2Y subtypes. An account of key functions mediated by purinoceptors follows, including examples of both short-term and long-term (trophic) signalling and a table showing the selective agonists and antagonists for the purinoceptor subtypes. References to evolution and roles of purinoceptors in pathological conditions are also presented.

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The author declares that he has no conflicts of interest.

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This article does not contain any studies with human participants or animals performed by the author.

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Authors and Affiliations

  1. University College London Medical School, London, UK

    Geoffrey Burnstock

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  1. Geoffrey Burnstock
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Correspondence to Geoffrey Burnstock .

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Editors and Affiliations

  1. Biochem and Mol Biol, Baylor College of Medicine, Houston, Texas, USA

    M. Zouhair Atassi

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Burnstock, G. (2017). Introduction to the Special Issue on Purinergic Receptors. In: Atassi, M. (eds) Protein Reviews. Advances in Experimental Medicine and Biology(), vol 1051. Springer, Singapore. https://doi.org/10.1007/5584_2017_12

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