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Hypertension in Pregnancy

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Hypertension: from basic research to clinical practice

Part of the book series: Advances in Experimental Medicine and Biology ((AIM,volume 956))

Abstract

Hypertensive disorders of pregnancy remain an unresolved and unpreventable problem in obstetrics. They remain one of the leading member of deadly triad causing maternal mortality, the other two being hemorrhage and sepsis which are preventable. The incidence of hypertensive disorders worldwide is 12 %. We have discussed various terminologies used to describe hypertension during pregnancy, risk factors, etiopathogenesis, pathophysiology, management guidelines, complications and long term consequences of hypertensive disorders of pregnancy in this chapter.

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References

  • ACOG Committee on Obstetric Practice (2002) Diagnosis and management of preeclampsia and eclampsia. ACOG Practice Bulletin No. 33. American College of Obstetricians and Gynaecologists. ObstetGynecol 99:159–167

    Google Scholar 

  • American College of Obstetrician and Gynecologists (2002) Obstetric analgesia and anaesthesia. Practice bulletin No. 36, July 2002, Reaffirmed 2013d.

    Google Scholar 

  • American College of Obstetricians and Gynecologists (2002) Diagnosis and management of preeclampsia- eclampsia. Practice Bulletin No. 33. January 2002, Reaffirmed 2012b.

    Google Scholar 

  • American College of Obstetricians and Gynecologists, Task Force on Hypertension in Pregnancy (2013) Hypertension in pregnancy. Report of the ACOG Task Force on Hypertension in Pregnancy. Obstetrics and Gynaecology 122:1122

    Google Scholar 

  • Askie LM, Henderson-Smart DJ, Stewart LA (2007) Antiplatelet agents for the prevention of preeclampsia: a meta-analysis of individual data. Lancet 369:179

    Article  Google Scholar 

  • Aukes AM, Wessel I, Dubois AM et al (2007) Self reported cognitive functioning in formerly eclamptic women. Am J Obstet Gynecol 197(4):365.e1

    Article  Google Scholar 

  • Aukes AM, de Groot JC, Aarnoudse JG et al (2009) Brain lesions several years after eclampsia. Am J Obstet Gynecol 200(5):504.e1

    Article  Google Scholar 

  • Aukes AM, de Groot JC, Weigman MJ et al (2012) Long- term cerebral imaging after preeclampsia. BJOG 119(9):1117

    Article  CAS  PubMed  Google Scholar 

  • Bramham K, Briley AL, Seed P et al (2011) Adverse maternal and perinatal outcomes in women with previous preeclampsia: a prospective study. Am J Obstet Gynecol 204(6):512.e1

    Article  Google Scholar 

  • Breastfeeding (2011) Hypertension in pregnancy: the management of hypertensive disorders during pregnancy. Nice clinical guidelines, No 107. RCOG

    Google Scholar 

  • Buurma AJ, Turner RJ, Driessen JH et al (2013) Genetic variants in preeclampsia: a meta analysis. Hum Reprod Update 19(3):289

    Article  CAS  PubMed  Google Scholar 

  • Committee Opinion No. 638 (2015) First-trimester risk assessment for early-onset preeclampsia. Obstet Gynecol 126(3):e25-7

    Google Scholar 

  • Conde-Augudelo A, Romero R, Roberts JM (2014) Tests to predict preeclampsia. In: Taylor RN, Roberts JM, Cunningham FG (eds) Chesley’s hypertensive disorders in pregnancy, 4th edn. Academic Press, Amsterdem

    Google Scholar 

  • Connealy B, Carrreno C, Kase B et al (2013) A history of prior preeclampsia is a major risk factor for preterm birth. Abstract No. 619. Am J Obstet Gynecol 208(1 Suppl):S264

    Article  Google Scholar 

  • Gastric MD, Gandhi SK, Pantazopoulos J et al (2012) Cardiovascular outcomes after preeclampsia or eclampsia complicated by myocardial infarction or stroke. Obstet Gynecol 120(4):823

    Article  Google Scholar 

  • Magpie Trial Collaboration Group (2002) Do women with preeclampsia, and their babies, benefit from magnesium sulphate? The Magpie Trial: a randomized placebo-controlled trial. Lancet 359:1877

    Google Scholar 

  • McMohan K, Karumanchi SA, Dammann O et al (2014) Does soluble fms-like tyrosine kinase-1 regulate placental invasion? Insight from the invasive placenta. Am J Obstet Gynaecol 10:66.e1

    Google Scholar 

  • Myatt L, Clifton RG, Roberts JM et al (2012a) First trimester prediction of preeclampsia in nulliparous women at low risk. Obstet Gynecol 119:6

    Article  Google Scholar 

  • Myatt L, Clifton RG, Roberts JM et al (2012b) The utility of uterine artery Doppler velocimetry in prediction of preeclampsia in a low risk population. Obstet Gynecol 120(4):815

    Article  PubMed  PubMed Central  Google Scholar 

  • National High Blood Pressure Education Program (2000) Working group report on high blood pressure in pregnancy. Am J Obstet Gynecol 183:51

    Google Scholar 

  • Nelson DB, Ziadie MS, McIntire DD et al (2014) Placental pathology suggesting that preeclampsia is more than one disease. Am J Obstet Gynaecol 210:66.e1

    Article  Google Scholar 

  • Roberts CL, Ford JB, Algert CS et al (2011) Population based trends in pregnancy hypertension and preeclampsia: an international comparative study. BMJ Open 1(1):e000101

    Article  PubMed  PubMed Central  Google Scholar 

  • Royal College of Obstetricians and Gynaecologists (2006) The management of severe preeclampsia. RCOG Guideline 10A:1

    Google Scholar 

  • Sheehan HL, Lynch JB (eds) (1973) Cerebral lesions. In: Patholgyof toxemia of pregnancy. Williams & Wilkins, Baltimore

    Google Scholar 

  • Sibai BM (2005) Diagnosis, prevention, and management of eclampsia. Obstet Gynecol 105:402

    Article  PubMed  Google Scholar 

  • Sibai BM (2012) Etiology and management of postpartum hypertension-preeclampsia. Am J Obstet Gynecol 206(6):470

    Article  PubMed  Google Scholar 

  • Sibai BM, Stella CL (2009) Diagnosis and management of atypical preeclampsia-eclampsia. Am J Obstet Gynecol 200:481.e1

    Article  Google Scholar 

  • Spaan JJ, Sep SJS, Lope van Balen V et al (2012) Metabolic syndrome as a risk factor for hypertension after preeclampsia. Obstet Gynecol 120(2 Pt 1):311

    Article  PubMed  Google Scholar 

  • Staff AC, Sibai BM, Cunningham FG (2014) Prevention of preeclampsia and eclampsia. In: Taylor RN, Roberts JM, Cunningham FG (eds) Chesley’s hypertensive disorders in pregnancy. Acedemic Press, Amsterdam

    Google Scholar 

  • Stains-Urias E, Paez MC, Doyle P et al (2012) Genetic association studies in preeclampsia; systemic meta-analyses and field synopsis. Int J Epidemiol 41(6):1764

    Article  Google Scholar 

  • Thorton C, Dahlen H, Korda A et al (2013) The incidence of preeclampsia and eclampsia and associated maternal mortality in Australia from population-linked datasets: 2000–2008. Am J Obstet Gynecol 208(6):476.e1

    Article  Google Scholar 

  • Vikse BE, Irgens LM, Leivestad T et al (2008) Preeclampsia and the risk of end-stage renal disease. N Engl J Med 359:800

    Article  CAS  PubMed  Google Scholar 

  • Walker JJ (2000) Pre-eclampsia. Lancet 356:1260–5

    Article  CAS  PubMed  Google Scholar 

  • Ward K, Taylor RN (2014) Genatic factors in etiology of preeclampsia. In: Taylor RN, Roberts JM, Cunningham FG (eds) Chesley’s hypertensive disorders in pregnancy, 4th edn. Acedemic Press, Amsterdam

    Google Scholar 

  • Weinstein L (1985) Preeclampsia- eclampsia with hemolysis, elevated liver enzymes and thrombocytopenia. Obstet Gynecol 66:657

    CAS  PubMed  Google Scholar 

  • Wikstrom AK, Haglund B, Olovsson M et al (2005) The risk of maternal ischemic heart disease after gestational hypertensive disease. BJOG 112:1486

    Article  PubMed  Google Scholar 

  • Zwart JJ, Richters A, Ory F et al (2008) Eclampsia in The Netherlands. Obstet Gynecol 112:820

    Article  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Department Obstetrics and Gynaecology, PGIMS, University of Health Sciences, Rohtak, Haryana, India

    Roopa Malik

  2. Department of Internal Medicine, PGIMS, University of Health Sciences, Rohtak, Haryana, India

    Viral Kumar

Authors
  1. Roopa Malik
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  2. Viral Kumar
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Corresponding author

Correspondence to Roopa Malik .

Editor information

Editors and Affiliations

  1. Department of Clinical Science and Education Södersjukhuset, Karolinska Institutet, Stockholm, Sweden

    Md. Shahidul Islam

  2. Department of Internal Medicine and Emergency Medicine, Uppsala University Hospital, Uppsala, Sweden

    Md. Shahidul Islam

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© 2016 Springer International Publishing AG

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Malik, R., Kumar, V. (2016). Hypertension in Pregnancy. In: Islam, M.S. (eds) Hypertension: from basic research to clinical practice. Advances in Experimental Medicine and Biology(), vol 956. Springer, Cham. https://doi.org/10.1007/5584_2016_150

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  • DOI: https://doi.org/10.1007/5584_2016_150

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-44250-1

  • Online ISBN: 978-3-319-44251-8

  • eBook Packages: MedicineMedicine (R0)

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