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Corticosteroids in Immunosuppression

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Pharmacology of Immunosuppression

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 272))

Abstract

Corticosteroids have been utilized as mainstay pharmacological intervention for successful organ transplantation since the beginning. Several challenges exist in establishing a balance between achieving a tolerant atmosphere in the host immune system while minimizing the long-term impact of steroids on the body. Corticosteroids are used early in all solid organ transplantation but there is wide variability across various organs and centers in the duration of use and protocols of planned steroid wean. The adverse event profile of steroids is exhaustive and across many organ systems.

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Author information

Authors and Affiliations

  1. Department of Cardiology, Section of Advanced Heart Failure, Mechanical Support Devices and Cardiac Transplantation, Houston Methodist Hospital, Houston, TX, USA

    Caroline Marzbani & Arvind Bhimaraj

Authors
  1. Caroline Marzbani
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  2. Arvind Bhimaraj
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Corresponding author

Correspondence to Arvind Bhimaraj .

Editor information

Editors and Affiliations

  1. Heart and Vascular Institute, Pennsylvania State University, Hershey, PA, USA

    Howard J. Eisen

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Marzbani, C., Bhimaraj, A. (2022). Corticosteroids in Immunosuppression. In: Eisen, H.J. (eds) Pharmacology of Immunosuppression. Handbook of Experimental Pharmacology, vol 272. Springer, Cham. https://doi.org/10.1007/164_2021_567

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