Abstract
Bone tissue engineering (BTE) is a transitional research field that focuses on material science and biology to construct novel biocomposites proficient in treating impaired bone. Bioactive molecules are unique therapeutic agents that have prompted rapid advances in the field of tissue engineering. Polymers of natural sources play a crucial role in the fabrication of biocompatible delivery systems that facilitate bioactive agents’ efficient delivery. Chitosan (CS) is known for its distinct pharmacological properties, and its function in regenerative medicine is well recorded. The versatility of CS enables the formulation of a wide range of drug carriers. This chapter highlights various scientific findings concerning different forms of nanomaterials produced from CS. CS-based composites’ utility as effective delivery systems for the potent bioactive compounds such as growth factors, nucleic acids, and phytocompounds in treating bone defects is discussed.
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Sidharthan, D.S., Abhinandan, R., Adithya, S.P., Balagangadharan, K., Selvamurugan, N. (2021). Chitosan and Its Potential Use for the Delivery of Bioactive Molecules in Bone Tissue Engineering. In: Jayakumar, R., Prabaharan, M. (eds) Chitosan for Biomaterials IV. Advances in Polymer Science, vol 288. Springer, Cham. https://doi.org/10.1007/12_2021_99
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