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Transition Metal-Catalyzed Enantioselective Hydrogenation of Enamides and Enamines

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Stereoselective Formation of Amines

Part of the book series: Topics in Current Chemistry ((TOPCURRCHEM,volume 343))

Abstract

Transition metal-catalyzed enantioselective hydrogenation of enamides and enamines is one of the most important methods for the preparation of optically active amines. This review describes the recent developments of highly efficient catalytic asymmetric hydrogenation of enamides, and enamines. It specifically focuses on the substrates because hydrogenation of enamides and enamines is highly dependent on the substrates although the chiral metal catalysts play a significant role.

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Authors and Affiliations

  1. State Key Laboratory and Institute of Elemento-Organic Chemistry, Nankai University, Tianjin, 300071, China

    Qi-Lin Zhou & Jian-Hua Xie

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  1. Qi-Lin Zhou
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  2. Jian-Hua Xie
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Correspondence to Qi-Lin Zhou .

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Editors and Affiliations

  1. Institute of Chemical Biology and Drug Discovery, Stony Brook University, Stony Brook, New York, USA

    Wei Li

  2. Department of Chemistry & Chemical Biology, Department of Medicinal Chemistry, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA

    Xumu Zhang

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Zhou, QL., Xie, JH. (2013). Transition Metal-Catalyzed Enantioselective Hydrogenation of Enamides and Enamines. In: Li, W., Zhang, X. (eds) Stereoselective Formation of Amines. Topics in Current Chemistry, vol 343. Springer, Berlin, Heidelberg. https://doi.org/10.1007/128_2013_482

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