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Structural Diversity, Electrochemical, and DNA-Binding Properties of Copper(II) Carboxylates

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Abstract

Extensive research is being devoted to the design and development of non-covalently DNA-binding drugs to overcome the side effects of covalently bonding platinum-based drugs. Moreover, several other factors determine the ability of a metal complex to become a successful bio-active agent. This short review highlights some of the features of copper(II) carboxylates which affect their ability to act as therapeutic agents in general and DNA-binding agents in specific.

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Authors and Affiliations

  1. Department of Chemistry, Bacha Khan University, Charsadda, KPK, Pakistan

    Muhammad Iqbal

  2. Department of Chemistry, Quaid-i-Azam University, Islamabad, 45320, Pakistan

    Saqib Ali & Ali Haider

  3. Chemistry Division, Pakistan Institute of Nuclear Science and Technology, P.O. Nilore, Islamabad, Pakistan

    Nasir Khalid

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Correspondence to Muhammad Iqbal or Saqib Ali.

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Iqbal, M., Ali, S., Haider, A. et al. Structural Diversity, Electrochemical, and DNA-Binding Properties of Copper(II) Carboxylates. Iran J Sci Technol Trans Sci 42, 1859–1871 (2018). https://doi.org/10.1007/s40995-016-0141-5

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  • DOI: https://doi.org/10.1007/s40995-016-0141-5

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