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Ubiquitination: a tool for plant adaptation to changing environments

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Abstract

Post-translational modifications namely ubiquitination, phosphorylation, methylation and acetylation play distinct roles in regulating the growth and development of plants. Among these, the ubiquitination regulates the abundance, activities, subcellular compartmentalization and trafficking of regulatory proteins involved in diverse developmental as well as stress-responsive processes. The ubiquitin–proteasome system (UPS) involves five essential components namely ubiquitin, ubiquitin-activating enzyme (E1), ubiquitin-conjugating enzyme (E2), ubiquitin ligase (E3) and the intact 26S proteasome. The E3 ubiquitin ligase is the major component of UPS that recognizes and tethers poly-ubiquitins on the target proteins. Owing to its specificity of substrate recognition, the E3 ubiquitin ligase contributes not only to the proteome plasticity of the cell but also regulates the plant’s response to environmental cues. In this context, the review summarizes the components involved in UPS and elaborates the role of E3 ubiquitin ligase in biotic and abiotic stress responses.

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Acknowledgments

Authors’ work in this area is financially supported by the Department of Biotechnology, Ministry of Science and Technology, Govt. of India (Project No.: BT/PR8357/PBD/16/1033/2013). AM acknowledges the NPDF award from DST-SERB, Govt. of India. MM acknowledges the DST INSPIRE Faculty Award from DST, Govt. of India. The authors are thankful to DBT-eLibrary Consortium (DeLCON) for providing access to the e-resources.

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  1. Department of Biotechnology, Maulana Abul Kalam Azad University of Technology, Kolkata, West Bengal, 700064, India

    Arunava Mandal

  2. National Institute of Plant Genome Research, Aruna Asaf Ali Marg, New Delhi, 110067, India

    Arunava Mandal, Namisha Sharma, Mehanathan Muthamilarasan & Manoj Prasad

  3. ICAR-National Research Centre on Plant Biotechnology, Pusa Campus, New Delhi, 110012, India

    Mehanathan Muthamilarasan

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  1. Arunava Mandal
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Correspondence to Manoj Prasad.

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This article is dedicated to the memory of Profs AK Sharma and Archana Sharma.

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Mandal, A., Sharma, N., Muthamilarasan, M. et al. Ubiquitination: a tool for plant adaptation to changing environments. Nucleus 61, 253–260 (2018). https://doi.org/10.1007/s13237-018-0255-6

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