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The influence of neighborhood socioeconomic status and ethnic enclave on endometrial cancer mortality among Hispanics and Asian Americans/Pacific Islanders in California

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Abstract

Purpose

We investigated the role of neighborhood socioeconomic status (nSES) and residence in ethnic enclaves on mortality following endometrial cancer (EC) diagnosis among Hispanics and Asian Americans/Pacific Islanders (AAPI).

Methods

Using California Cancer Registry data, enhanced with census block group information on ethnic enclave and nSES, we examined 9,367 Hispanics and 5,878 AAPIs diagnosed with EC from 1988 to 2011. Cox proportional hazard models were used to estimate associations between all-cause and EC-specific mortality with nSES and ethnic enclaves, adjusting for subject sociodemographic and tumor characteristics.

Results

Hispanics in the lowest SES neighborhoods had a 39% and 36% increased risk of all-cause and EC-specific mortality, respectively, compared to Hispanics in the highest SES neighborhoods. AAPIs in the lowest SES neighborhoods had a 37% increased risk of all-cause mortality compared to AAPIs in the highest SES neighborhoods. Living in an ethnic enclave was associated with lower all-cause mortality risk for AAPIs.

Conclusions

Mortality risk varied by nSES and ethnic enclave among Hispanics and AAPIs. Women living in lower SES communities experienced significantly higher risk, highlighting the need to identify the specific neighborhood factors underlying these associations so that community-based interventions may be properly targeted.

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Funding

Funding was provided by National Cancer Institute, Surveillance, Epidemiology and End Results Program (Grant Nos. HHSN261201000140C, HHSN261201000035C, HHSN261201000034C) and Centers for Disease Control and Prevention’s National Program of Cancer Registries (Grant No. U58DP003862-01).

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Author notes

  1. Julie Von Behren and Renata Abrahão contributed equally to the manuscript.

Authors and Affiliations

  1. Greater Bay Area Cancer Registry, Cancer Prevention Institute of California, 2201 Walnut Ave, Suite 300, Fremont, CA, 94538, USA

    Julie Von Behren, Renata Abrahão, Debbie Goldberg, Scarlett Lin Gomez & Iona Cheng

  2. Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA

    Julie Von Behren, Debbie Goldberg, Scarlett Lin Gomez & Iona Cheng

  3. Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA

    Veronica Wendy Setiawan

Authors
  1. Julie Von Behren
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  2. Renata Abrahão
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  3. Debbie Goldberg
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  4. Scarlett Lin Gomez
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  5. Veronica Wendy Setiawan
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  6. Iona Cheng
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Corresponding author

Correspondence to Julie Von Behren.

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The authors declare that they have no conflict of interest.

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Von Behren, J., Abrahão, R., Goldberg, D. et al. The influence of neighborhood socioeconomic status and ethnic enclave on endometrial cancer mortality among Hispanics and Asian Americans/Pacific Islanders in California. Cancer Causes Control 29, 875–881 (2018). https://doi.org/10.1007/s10552-018-1063-7

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  • DOI: https://doi.org/10.1007/s10552-018-1063-7

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