Skip to main content

Advertisement

Log in

Project nGage: Results of a Randomized Controlled Trial of a Dyadic Network Support Intervention to Retain Young Black Men Who Have Sex With Men in HIV Care

  • Original Paper
  • Published:
AIDS and Behavior Aims and scope Submit manuscript

Abstract

HIV-positive young black MSM (YBMSM) experience poor outcomes along the HIV care continuum, yet few interventions have been developed expressly for YBMSM retention in care. Project nGage was a randomized controlled trial conducted across five Chicago clinics with 98 HIV-positive YBMSM aged 16–29 between 2012 and 2015. The intervention used a social network elicitation approach with index YBMSM (n = 45) to identify and recruit a support confidant (SC) to the study. Each index-SC dyad met with a social worker to improve HIV-care knowledge, activate dyadic social support, and develop a retention in care plan. Each index and SC also received four mini-booster sessions. Control participants (n = 53) received treatment as usual. Surveys and medical records at baseline, 3-, and 12-months post-intervention assessed visit history (3 or more visits over 12 months; primary outcome), and sociodemographic, network, social-psychological, and behavioral factors. At baseline, there were no differences in age (M = 23.8 years), time since diagnosis (M ≤ 2 years), clinic visits in the previous 12 months (M = 4.1), and medication adherence (68.6 ≥ 90% adherence). In multivariate logistic regression analysis, intervention participants were 3.01 times more likely to have had at least 3 provider visits (95% CI 1.0–7.3) than were control participants over 12 months. Project nGage demonstrates preliminary efficacy in improving retention in care among YBMSM. Results suggest that engaging supportive network members may improve key HIV care continuum outcomes.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  1. Gardner EM, McLees MP, Steiner JF, del Rio C, Burman WJ. The spectrum of engagement in HIV care and its relevance to test-and-treat strategies for prevention of HIV infection. Clin Infect Dis. 2011;52(6):793–800.

    Article  PubMed  PubMed Central  Google Scholar 

  2. Hull MW, Wu Z, Montaner JS. Optimizing the engagement of care cascade: a critical step to maximize the impact of HIV treatment as prevention. Curr Opin HIV AIDS. 2012;7(6):579–86.

    Article  PubMed  Google Scholar 

  3. Whiteside YO, Cohen SM, Bradley H, Skarbinski J, Hall HI, Lansky A. Progress along the continuum of HIV care among blacks with diagnosed HIV—United States, 2010. MMWR Morb Mortal Wkly Rep. 2014;63(5):85–9.

    PubMed  Google Scholar 

  4. Singh S, Bradley H, Hu X, Skarbinski J, Hall HI, Lansky A. Men living with diagnosed HIV who have sex with men: progress along the continuum of HIV care—United States, 2010. MMWR Morb Mortal Wkly Rep. 2014;63(38):829–33.

    PubMed  Google Scholar 

  5. Campsmith ML, Rhodes PH, Hall HI, Green TA. Undiagnosed HIV prevalence among adults and adolescents in the United States at the end of 2006. J Acquir Immune Defic Syndr. 2010;53:619–24.

    PubMed  Google Scholar 

  6. Traeger L, O’Cleirigh C, Skeer MR, Mayer KH, Safren SA. Risk factors for missed HIV primary care visits among men who have sex with men. J Behav Med. 2011;35:548–56.

    Article  PubMed  PubMed Central  Google Scholar 

  7. Giordano TP, Gifford AL, White AC Jr, Suarez-Almazor ME, Rabeneck L, Hartman C, et al. Retention in care: a challenge to survival with HIV infection. Clin Infect Dis. 2007;44(11):1493–9.

    Article  PubMed  Google Scholar 

  8. Ford MA, Spicer CM. Monitoring HIV care in the United States: indicators and data systems. Washington, DC: National Academies Press; 2012.

    Google Scholar 

  9. Duncan KC, Salters K, Forrest JI, Palmer AK, Wang H, O’Brien N, et al. Cohort profile: longitudinal investigations into supportive and ancillary health services. Int J Epidemiol. 2013;42(4):947–55.

    Article  PubMed  Google Scholar 

  10. O’Neil CR, Palmer AK, Coulter S, O’Brien N, Shen A, Zhang W, et al. Factors associated with antiretroviral medication adherence among HIV-positive adults accessing highly active antiretroviral therapy (HAART) in British Columbia, Canada. J Int Assoc Physicians AIDS Care (JIAPAC). 2012;11:134–41.

    Article  Google Scholar 

  11. Prejean J, Song R, Hernandez A, Ziebell R, Green T, Walker F, HIV Incidence Surveillance Group. Estimated HIV incidence in the United States, 2006–2009. PLoS ONE. 2011;6(8):e17502.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  12. Bouris A, Voisin D, Pilloton M, Flatt N, Eavou R, Hampton K, et al. Project nGage: network supported HIV care engagement for younger black men who have sex with men and transgender persons. J AIDS Clin Res. 2013;4:236.

    Google Scholar 

  13. Millett GA, Flores SA, Peterson JL, Bakeman R. Explaining disparities in HIV infection among black and white men who have sex with men: a meta-analysis of HIV risk behaviors. AIDS. 2007;21:2083–91.

    Article  PubMed  Google Scholar 

  14. Voisin DR, DiClemente RJ, Salazar LF, Crosby RA, Yarber WL. Ecological factors associated with STD risk behaviors among detained female adolescents. Soc Work. 2006;51(1):71–9.

    Article  PubMed  Google Scholar 

  15. Voisin DR, Salazar LF, Crosby R, Diclemente RJ, Yarber WL, Staples-Horne M. Teacher connectedness and health-related outcomes among detained adolescents. J Adolesc Health. 2005;37(4):337.

    Article  PubMed  Google Scholar 

  16. Mo PKH, Coulson NS. Exploring the communication of social support within virtual communities: a content analysis of messages posted to an online HIV/AIDS support group. Cyber Psychol Behav. 2008;11(3):371–4.

    Article  Google Scholar 

  17. Berg KM, Wilson IB, Li X, Arnsten JH. Comparison of antiretroviral adherence questions. AIDS Behav. 2010;16:461–8.

    Article  Google Scholar 

  18. Magnus M, Jones K, Phillips G 2nd, Binson D, Hightow-Weidman LB, Richards-Clarke C, et al. Characteristics associated with retention among African American and Latino adolescent HIV-positive men: results from the outreach, care, and prevention to engage HIV-seropositive young MSM of color special project of national significance initiative. J Acquir Immune Defic Syndr. 2010;53(4):529–36.

    Article  PubMed  Google Scholar 

  19. Hightow-Weidman LB, Jones K, Wohl AR, Futterman D, Outlaw A, Phillips G, et al. Early linkage and retention in care: findings from the outreach, linkage, and retention in care initiative among young men of color who have sex with men. AIDS Patient Care STDS. 2011;25(Suppl 1):S31–8.

    Article  PubMed  Google Scholar 

  20. Schwarzer R, Dunkel-Schetter C, Kemeny M. The multidimensional nature of received social support in gay men at risk of HIV infection and AIDS. Am J Community Psychol. 1994;22(3):319–39.

    Article  CAS  PubMed  Google Scholar 

  21. Detrie PM, Lease SH. The relation of social support, connectedness, and collective self-esteem to the psychological well-being of lesbian, gay, and bisexual youth. J Homosex. 2007;53(4):173–99.

    Article  PubMed  Google Scholar 

  22. Simoni JM, Huh D, Frick PA, Pearson CR, Andrasik MP, Dunbar PJ, et al. Peer support and pager messaging to promote antiretroviral modifying therapy in Seattle: a randomized controlled trial. J Acquir Immune Defic Syndr. 2009;52(4):465–73.

    Article  PubMed  PubMed Central  Google Scholar 

  23. Remien RH, Stirratt MJ, Dolezal C, Dognin JS, Wagner GJ, Carballo-Dieguez A, et al. Couple-focused support to improve HIV medication adherence: a randomized controlled trial. AIDS. 2005;19(8):807–14.

    Article  PubMed  Google Scholar 

  24. Simoni JM, Pantalone DW, Plummer MD, Huang B. A randomized controlled trial of a peer support intervention targeting antiretroviral medication adherence and depressive symptomatology in HIV-positive men and women. Health Psychol. 2007;26(4):488.

    Article  PubMed  PubMed Central  Google Scholar 

  25. Kelly JA, St Lawrence JS, Diaz YE, Stevenson LY, Hauth AC, Brasfield TL, et al. HIV risk behavior reduction following intervention with key opinion leaders of population: an experimental analysis. Am J Public Health. 1991;81(2):168–71.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  26. Kegeles SM, Hays RB, Coates TJ. The Mpowerment project: a community-level HIV prevention intervention for young gay men. Am J Public Health. 1996;86(8 Pt 1):1129–36.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  27. Kimbrough LW, Fisher HE, Jones KT, Johnson W, Thadiparthi S, Dooley S. Accessing social networks with high rates of undiagnosed HIV infection: the social networks demonstration project. Am J Public Health. 2009;99(6):1093–9.

    Article  PubMed  PubMed Central  Google Scholar 

  28. Kelly JD, Hartman C, Graham J, Kallen MA, Giordano TP. Social support as a predictor of early diagnosis, linkage, retention, and adherence to HIV care: results from the steps study. J Assoc Nurses AIDS Care. 2014;25(5):405–13.

    Article  PubMed  PubMed Central  Google Scholar 

  29. Wohl AR, Galvan FH, Myers HF, Garland W, George S, Witt M, et al. Do social support, stress, disclosure and stigma influence retention in HIV care for Latino and African American men who have sex with men and women? AIDS Behav. 2011;15(6):1098–110.

    Article  PubMed  Google Scholar 

  30. Catz SL, McClure JB, Jones GN, Brantley PJ. Predictors of outpatient medical appointment attendance among persons with HIV. AIDS Care. 1999;11(3):361–73.

    Article  CAS  PubMed  Google Scholar 

  31. Mannheimer S, Hirsch-Moverman Y. What we know and what we do not know about factors associated with and interventions to promote antiretroviral adherence. Curr Infect Dis Rep. 2015;17(4):1–8.

    Article  Google Scholar 

  32. Iroh PA, Mayo H, Nijhawan AE. The HIV care cascade before, during, and after incarceration: a systematic review and data synthesis. Am J Public Health. 2015;105(7):e5–16.

    Article  PubMed  PubMed Central  Google Scholar 

  33. Bekker L-G, Johnson L, Wallace M, Hosek S. Building our youth for the future. J Int AIDS Soc. 2015;18:1–7.

    Google Scholar 

  34. Hogan B, Carrasco JA, Wellman B. Visualizing personal networks: working with participant-aided sociograms. Field Method. 2007;19(2):116–44.

    Article  Google Scholar 

  35. McFadden RB, Bouris AM, Voisin DR, Glick NR, Schneider JA. Dynamic social support networks of younger black men who have sex with men with new HIV infection. AIDS Care. 2014;26(10):1275–82.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  36. Harris PA, Taylor R, Thielke R, Payne J, Gonzalez N, Conde JG. Research electronic data capture (REDCap)—a metadata-driven methodology and workflow process for providing translational research informatics support. J Biomed Inform. 2009;42(2):377–81.

    Article  PubMed  Google Scholar 

  37. Fisher JD, Fisher WA, Amico KR, Harman JJ. An information–motivation–behavioral skills model of adherence to antiretroviral therapy. Health Psychol. 2006;25(4):462.

    Article  PubMed  Google Scholar 

  38. Starace F, Massa A, Amico KR, Fisher JD. Adherence to antiretroviral therapy: an empirical test of the information-motivation-behavioral skills model. Health Psychol. 2006;25(2):153.

    Article  PubMed  Google Scholar 

  39. Miller WR, Rollnick S. Motivational interviewing: helping people change. 3rd ed. New York: The Guilford Press; 2012.

    Google Scholar 

  40. Safren SA, O’Cleirigh C, Tan JY, Raminani SR, Reilly LC, Otto MW, et al. A randomized controlled trial of cognitive behavioral therapy for adherence and depression (CBT-AD) in HIV-infected individuals. Health Psychol. 2009;28(1):1–10.

    Article  PubMed  PubMed Central  Google Scholar 

  41. Safren SGJ, Soroudi N. Coping with chronic illness: a cognitive-behavioral approach for adherence and depression: therapist guide. New York: Oxford University Press; 2007.

    Book  Google Scholar 

  42. Christopoulos KA, Das M, Colfax GN. Linkage and retention in HIV care among men who have sex with men in the United States. Clin Infect Dis. 2011;52(Suppl 2):S214–22.

    Article  PubMed  PubMed Central  Google Scholar 

  43. Mugavero MJ, Westfall AO, Zinski A, Davila J, Drainoni M-L, Gardner LI, et al. Measuring retention in HIV care: the elusive gold standard. J Acquir Immune Defic Syndr. 2012;61(5):574.

    Article  PubMed  PubMed Central  Google Scholar 

  44. Kuhns LM, Hotton AL, Garofalo R, Muldoon AL, Jaffe K, Bouris A, et al. An index of multiple psychosocial, syndemic conditions is associated with antiretroviral medication adherence among HIV-positive youth. AIDS Patient Care STD. 2016;30(4):185–92.

    Article  Google Scholar 

  45. Murphy DA, Sarr M, Durako SJ, Moscicki A-B, Wilson CM, Muenz LR. Barriers to HAART adherence among human immunodeficiency virus–infected adolescents. Arch Pediat Adol Med. 2003;157(3):249–55.

    Article  Google Scholar 

  46. Paterson DL, Swindells S, Mohr J, Brester M, Vergis EN, Squier C, et al. Adherence to protease inhibitor therapy and outcomes in patients with HIV infection. Ann Intern Med. 2000;133(1):21–30.

    Article  CAS  PubMed  Google Scholar 

  47. Schneider JA, Cornwell B, Ostrow D, Michaels S, Schumm P, Laumann EO, et al. Network mixing and network influences most linked to HIV infection and risk behavior in the HIV epidemic among black men who have sex with men. Am J Public Health. 2013;103(1):e28–36.

    Article  PubMed  PubMed Central  Google Scholar 

  48. Schneider J, Michaels S, Bouris A. Family network proportion and HIV risk among black men who have sex with men. J Acquir Immune Defic Syndr. 2012;61(5):627.

    Article  PubMed  PubMed Central  Google Scholar 

  49. Outlaw A, Naar-King S, Green-Jones M, Wright K, Condon K, Sherry L, et al. Brief report: predictors of optimal HIV appointment adherence in minority youth: a prospective study. J Pediatr Psychol. 2010;35(9):1011–5.

    Article  PubMed  Google Scholar 

  50. Wright K, Naar-King S, Lam P, Templin T, Frey M. Stigma scale revised: reliability and validity of a brief measure of stigma for HIV + youth. J Adolescent Health. 2007;40(1):96–8.

    Article  Google Scholar 

  51. Derogatis L. Brief symptom inventory: administration, scoring, and procedures manual. Minneapolis, MN: National Computer Systems Inc.; 1993.

    Google Scholar 

  52. Group WHO. The alcohol, smoking and substance involvement screening test (ASSIST): development, reliability and feasibility. Addiction. 2002;97(9):1183–94.

    Article  Google Scholar 

  53. Bouris A, Hill BJ, Fisher K, Erickson G, Schneider JA. Mother–son communication about sex and routine human immunodeficiency virus testing among younger men of color who have sex with men. J Adolescent Health. 2015;57(5):515–22.

    Article  Google Scholar 

  54. Park W, Choe P, Kim SH, Jo J, Bang J, Kim H, et al. One-year adherence to clinic visits after highly active antiretroviral therapy: a predictor of clinical progress in HIV patients. J Intern Med. 2007;261(3):268–75.

    Article  CAS  PubMed  Google Scholar 

  55. Mugavero MJ, Lin H-Y, Willig JH, Westfall AO, Ulett KB, Routman JS, et al. Missed visits and mortality among patients establishing initial outpatient HIV treatment. Clin Infect Dis. 2009;48(2):248–56.

    Article  PubMed  PubMed Central  Google Scholar 

  56. Magnus M, Jones K, Phillips G, Binson D, Hightow-Weidman LB, Richards-Clarke C, et al. Characteristics associated with retention among African American and Latino adolescent HIV-positive men: results from the outreach, care, and prevention to engage HIV-seropositive young MSM of color special project of national significance initiative. JAIDS J Acquir Immune Defic Syndr. 2010;53(4):529–36.

    Article  PubMed  Google Scholar 

  57. Woods ER. Overview of the special projects of national significance program’s 10 models of adolescent HIV care. J Adolescent Health. 1998;23(2):5–10.

    Article  CAS  Google Scholar 

  58. Lee L, Yehia BR, Gaur AH, Rutstein R, Gebo K, Keruly JC, et al. The impact of youth-friendly structures of care on retention among HIV-infected youth. AIDS Patient Care STDS. 2016;30(4):170–7.

    Article  PubMed  PubMed Central  Google Scholar 

  59. Kennedy DP, Hunter SB, Osilla KC, Maksabedian E, Golinelli D, Tucker JS. A computer-assisted motivational social network intervention to reduce alcohol, drug and HIV risk behaviors among Housing First residents. Addict Sci Clin Pract. 2016;11:4.

    Article  PubMed  PubMed Central  Google Scholar 

  60. Osilla KC, Kennedy DP, Hunter SB, Maksabedian E. Feasibility of a computer-assisted social network motivational interviewing intervention for substance use and HIV risk behaviors for housing first residents. Addict Sci Clin Pract. 2016;11:14.

    Article  PubMed  PubMed Central  Google Scholar 

  61. Schneider JCB, Jonas A, Behler R, Lancki N, Skaathun B, Michaels S, Khanna AS, Young LE, Morgan E, Duvoisin R, Friedman S, Schumm P, Laumann E, for the uConnect Study Team. Network dynamics and HIV risk and prevention in a population-based cohort of young Black men who have sex with men. Netw Sci. 2017;5:381–409.

    Article  Google Scholar 

  62. Valente TW. Social networks and health: models, methods, and applications. Oxford: Oxford University Press; 2010.

    Book  Google Scholar 

  63. Valente TW. Network interventions. Science. 2012;337(6090):49–53.

    Article  CAS  PubMed  Google Scholar 

  64. Schneider JA, Zhou AN, Laumann EO. A new HIV prevention network approach: sociometric peer change agent selection. Soc Sci Med. 2015;125:192–202.

    Article  PubMed  Google Scholar 

  65. Group NCHSPT. Results of the NIMH collaborative HIV/STD prevention trial of a community popular opinion leader intervention. J Acquir Immune Defic Syndr. 2010;54(2):204.

    Google Scholar 

  66. Schneider JA, McFadden RB, Laumann EO, Kumar SP, Gandham SR, Oruganti G. Candidate change agent identification among men at risk for HIV infection. Soc Sci Med. 2012;75(7):1192–201.

    Article  PubMed  PubMed Central  Google Scholar 

  67. Latkin C, Donnell D, Liu TY, Davey-Rothwell M, Celentano D, Metzger D. The dynamic relationship between social norms and behaviors: the results of an HIV prevention network intervention for injection drug users. Addiction. 2013;108(5):934–43.

    Article  PubMed  PubMed Central  Google Scholar 

  68. Valente TW. Network models of the diffusion of innovations. Comput Math Organ Theory. 1996;2(2):163–4.

    Article  Google Scholar 

Download references

Acknowledgements

This work was supported by the National Institute of Mental Health (R34MH097622, R01DA039934 and R01DA033875). ClinicalTrials.gov Identifier: NCT01726712. This manuscript was also made possible with help from the Third Coast Center for AIDS Research (P30 AI 117943). We would like to thank the study participants for their participation and Milton “Mickey” Eder, Molly Pilloton, Natasha Flatt, Tim Walsh, Tiffany Washington, Keisha Hampton and Montre Washington for their valuable contributions to the project.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Alida Bouris.

Ethics declarations

Conflicts of interest

The authors have no conflicts of interest to declare.

Ethical Approval

All protocols and policies for this study were approved by the Institutional Review Board at the University of Chicago. All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed Consent

Informed consent was obtained from all individual participants included in the study.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Bouris, A., Jaffe, K., Eavou, R. et al. Project nGage: Results of a Randomized Controlled Trial of a Dyadic Network Support Intervention to Retain Young Black Men Who Have Sex With Men in HIV Care. AIDS Behav 21, 3618–3629 (2017). https://doi.org/10.1007/s10461-017-1954-8

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10461-017-1954-8

Keywords

Navigation