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The outcomes and risk factors of early readmission in patients with intestinal Behçet’s disease

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Abstract

Hospital readmission rate is an integral quality of care measurement for hospitalized patients which is unknown for intestinal Behçet’s disease cases. The purpose of this study was to investigate the risk factors and outcomes for patients readmitted early with intestinal Behçet’s disease. We retrospectively reviewed patients with intestinal Behçet’s disease who were readmitted to our hospital between 2005 and 2016. We then analyzed the risk factors and outcomes for early readmission within 3 months. Of the 204 patients who were readmitted, 103 patients (50.5%) were readmitted within 3 months and 101 (49.5%) were never readmitted or readmitted after 3 months. After multivariate analysis, hospital stay at the first admission (adjusted odds ratio [OR], 0.945; 95% confidence interval [CI], 0.908–0.982; P = 0.004), high disease activity index for intestinal Behçet’s disease score (adjusted OR, 1.111; 95% CI, 1.060–1.165; P < 0.001), corticosteroid use (adjusted OR, 3.179; 95% CI, 1.135–8.910; P = 0.028), and opioid use (adjusted OR, 7.979; 95% CI, 1.084–58.755; P = 0.041) were independent factors for early readmission. We identified four independent prognostic factors for early readmission within 3 months, which might help guide appropriate management strategies for hospitalized patients with intestinal Behçet’s disease.

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Abbreviations

BD:

Behçet’s disease

GI:

Gastrointestinal

IBD:

Inflammatory bowel disease

CD:

Crohn’s disease

UC:

Ulcerative colitis

DAIBD:

Disease activity index for intestinal Behçet’s disease

ESR:

Erythrocyte sedimentation rate

CRP:

C-reactive protein

5-ASA:

5-Aminosalicylic acid

6-MP:

6-Mercaptopurine

NSAIDs:

Nonsteroidal anti-inflammatory drugs

IQR:

Interquartile range

ORs:

Odds ratios

CIs:

Confidence intervals

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Acknowledgements

The authors are grateful to Dong-Su Jang, (medical illustrator, Medical Research Support Section, Yonsei University College of Medicine, Seoul, Republic of Korea) for his help with the figures.

Guarantor of the article

Jae Hee Cheon.

Funding

This research was supported by a grant (A120176) from the Korean Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), which is funded by the Ministry of Health and Welfare, Republic of Korea; a grant (NRF-2017R1A1A1A05001011) from the Basic Science Research Program through the National Research Foundation of Korea, which is funded by the Ministry of Science, ICT and Future Planning; and a faculty research grant (2012-31-0477) from the Department of Internal Medicine, Yonsei University, College of Medicine.

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Authors and Affiliations

  1. Department of Internal Medicine, College of Medicine, Yonsei University, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea

    Yong Eun Park, Jae Hee Cheon, Yehyun Park, Soo Jung Park, Tae Il Kim & Won Ho Kim

  2. Institute of Gastroenterology, College of Medicine, Yonsei University, Seoul, South Korea

    Jae Hee Cheon, Yehyun Park, Soo Jung Park, Tae Il Kim & Won Ho Kim

Authors
  1. Yong Eun Park
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  2. Jae Hee Cheon
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  3. Yehyun Park
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  4. Soo Jung Park
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  5. Tae Il Kim
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  6. Won Ho Kim
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Contributions

Yong Eun Park: acquisition of data, analysis and interpretation of data, drafting of the manuscript. Yehyun Park: study concept and design, critical revision of the manuscript for important intellectual content. Soo Jung Park: study concept and design, critical revision of the manuscript for important intellectual content. Tae Il Kim: study concept and design, critical revision of the manuscript for important intellectual content. Won Ho Kim: study concept and design, critical revision of the manuscript for important intellectual content. Jae Hee Cheon: acquisition of data, study concept and design, critical revision of the manuscript for important intellectual content. All authors approved the final version of the article, including the authorship list.

Corresponding author

Correspondence to Jae Hee Cheon.

Ethics declarations

This study was performed in accordance with the ethical guidelines of the 1975 Declaration of Helsinki and approved by the Institutional Review Board of Severance Hospital.

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None.

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Park, Y.E., Cheon, J.H., Park, Y. et al. The outcomes and risk factors of early readmission in patients with intestinal Behçet’s disease. Clin Rheumatol 37, 1913–1920 (2018). https://doi.org/10.1007/s10067-017-3904-2

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  • DOI: https://doi.org/10.1007/s10067-017-3904-2

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