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The G1691A mutation of the coagulation factor V gene (factor V Leiden) is rare in Chinese: an analysis of 618 individuals

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Abstract

To understand the allele frequency of the G1691A mutation of the coagulation factor V gene (factor V Leiden) in Chinese, 618 Chinese individuals, including 54 cases with venous thrombosis, were analyzed. Only one case in the control group was heterozygous for the 1691G allele and the 1691A allele. Our data suggest that the factor V Leiden is rare in Chinese.

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Authors and Affiliations

  1. The First Cardiovascular Division, Department of Internal Medicine, Chang Gung Memorial Hospital, 199 Tung-Hwa North Road Taipei, Taiwan, Republic of China Tel.: +886-3-3281200 ext. 2313,8171; Fax: +886-3-3271192, , , , , , TW

    Y.-L. Ko, Tsu-Shiu Hsu, Shy-Meeng Wu, Yu-Shien Ko, Chi-Jen Chang, Shu-Mei Wang, Wei-Jan Chen, N.-J. Cheng, Chi-Tai Kuo, Chen-Wen Chiang & Ying-Shiung Lee

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  1. Y.-L. Ko
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  2. Tsu-Shiu Hsu
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  3. Shy-Meeng Wu
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  4. Yu-Shien Ko
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  5. Chi-Jen Chang
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  6. Shu-Mei Wang
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  7. Wei-Jan Chen
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  8. N.-J. Cheng
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  9. Chi-Tai Kuo
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  10. Chen-Wen Chiang
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  11. Ying-Shiung Lee
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Received: 5 February 1996 / Revised: 20 March 1996

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Ko, YL., Hsu, TS., Wu, SM. et al. The G1691A mutation of the coagulation factor V gene (factor V Leiden) is rare in Chinese: an analysis of 618 individuals. Hum Genet 98, 176–177 (1996). https://doi.org/10.1007/s004390050184

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  • DOI: https://doi.org/10.1007/s004390050184

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