Skip to main content
SpringerLink
Log in

Biomarker cruises in sepsis: who is the CAPTAIN? Discussion on “Circulating biomarkers may be unable to detect infection at the early phase of sepsis in ICU patients: the CAPTAIN prospective multicenter cohort study”

  • Correspondence
  • Published:
Intensive Care Medicine Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Parlato M, Philippart F, Rouquette A et al (2018) Circulating biomarkers may be unable to detect infection at the early phase of sepsis in ICU patients: the CAPTAIN prospective multicenter cohort study. Intensive Care Med 44:1061–1070. https://doi.org/10.1007/s00134-018-5228-3

    Article  CAS  PubMed  Google Scholar 

  2. Tavladaki T, Spanaki AM, Dimitriou H et al (2017) Similar metabolic, innate immunity, and adipokine profiles in adult and pediatric sepsis versus systemic inflammatory response syndrome—a pilot study. Pediatr Crit Care Med 18:e494–e505. https://doi.org/10.1097/PCC.0000000000001300

    Article  PubMed  Google Scholar 

  3. De Waele JJ, Akova M, Antonelli M et al (2018) Antimicrobial resistance and antibiotic stewardship programs in the ICU: insistence and persistence in the fight against resistance. A position statement from ESICM/ESCMID/WAAAR round table on multi-drug resistance. Intensive Care Med 44:189–196. https://doi.org/10.1007/s00134-017-5036-1

    Article  PubMed  Google Scholar 

  4. Vardas K, Apostolou K, Briassouli E et al (2014) Early response roles for prolactin cortisol and circulating and cellular levels of heat shock proteins 72 and 90α in severe sepsis and SIRS. Biomed Res Int 2014:803561. https://doi.org/10.1155/2014/803561

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Parlato M, Cavaillon J-M (2015) Host response biomarkers in the diagnosis of sepsis: a general overview. Methods Mol Biol 1237:149–211. https://doi.org/10.1007/978-1-4939-1776-1_15

    Article  CAS  PubMed  Google Scholar 

  6. Adib-Conquy M, Cavaillon J-M (2007) Stress molecules in sepsis and systemic inflammatory response syndrome. FEBS Lett 581:3723–3733. https://doi.org/10.1016/j.febslet.2007.03.074

    Article  CAS  PubMed  Google Scholar 

  7. Sager R, Wirz Y, Amin D et al (2017) Are admission procalcitonin levels universal mortality predictors across different medical emergency patient populations? Results from the multi-national, prospective, observational TRIAGE study. Clin Chem Lab Med 55:1873–1880. https://doi.org/10.1515/cclm-2017-0144

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgements

Members of the Combined Approach for The eArly diagnosis of INfection in sepsis (CAPTAIN) study group:

Sébastien JACQMIN, Didier JOURNOIS, Alix LAGRANGE, Gabrielle PINOT de VILLECHENON (Hôpital Européen Georges Pompidou, AP – HP - Université Paris Descartes, Service d’Anesthésie-Réanimation), Nadia AISSAOUI, Jean-Luc DIEHL, Emmanuel GUEROT, Marion VENOT (Hôpital Européen Georges Pompidou, AP – HP - Université Paris Descartes, Service de Réanimation Médicale), Olfa HAMZAOUI, Dominique PRAT, Benjamin SZTRYMF (Hôpital Antoine Béclère, AP – HP -Université Paris Sud, Clamart), Djillali ANNANE, Virginie MAXIME, Andrea POLITO (Hôpital Raymond Poincaré, AP – HP -Université Paris Ile de France Ouest , Service de Réanimation Médico-chirurgicale), Belaïd BOUHEMAD, Cédric BRUEL, Frédéric ETHUIN, Julien FOURNIER, Maïté GARROUSTE-ORGEAS, Charles GREGOIRE, Nicolas LAU, Benoît MISSET, François PHILIPPART (Groupe Hospitalier Paris Saint Joseph, Service de Réanimation), Jean-Pierre BEDOS, Pierrick CROSNIER, Virginie LAURENT, Sybille MERCERON (Hôpital André Mignot, Versailles, Service de Réanimation médicochirurgicale), Elsa BOURNAUD, Laurence LECOMTE, Jean-Marc TRELUYER, (Hôpital Cochin, AP-HP - Université Paris Descartes, Unité de Recherche Clinique), Alexandre PACHOT, Javier YUGUEROS-MARCOS, Laurent ESTEVE, Sophie BLEIN, Virginie MOUCADEL (bioMérieux, Lyon & Grenoble), Myriam BEN BOUTIEB, Alexandra ROUQUETTE, Joël COSTE (Hôpital Hotel-Dieu, AP-HP - Université Paris Descartes, Unité de Biostatistique et d’Epidémiologie), Minou ADIB-CONGUY, Jean-Marc CAVAILLON, Catherine FITTING, Marianna PARLATO, Virginie PUCHOIS, Fernando SOUZA-FONSECA GUIMARAES (Institut Pasteur, Paris, Unit Cytokines & Inflammation).

Author information

Authors and Affiliations

  1. Pediatric Intensive Care Unit, Faculty of Medicine, University Hospital, University of Crete, 71110, Heraklion, Crete, Greece

    George Briassoulis, Panagiotis Briassoulis, Marianna Miliaraki & Stavroula Ilia

  2. Laboratory of Intestinal Immunity and Institut Imagine, INSERM, UMR1163, Paris, France

    Marianna Parlato

  3. Service de Médecine Intensive et Réanimation, Groupe Hospitalier Paris Saint-Joseph, Paris, France

    François Philippart

  4. Unité Endotoxines Structures et Réponse de l’hôte, Département de Microbiologie, Institut de Biologie Intégrative de la Cellule, Université Paris-Saclay, Saclay, France

    François Philippart

  5. Service de Santé Publique et d’Épidémiologie, Hôpital du Kremlin-Bicêtre, CHU de Bicêtre, Assistance Publique, Hôpitaux de Paris, Bicêtre, France

    Alexandra Rouquette

  6. CESP, INSERM, Université Paris-Sud, UVSQ, Université Paris-Saclay, Paris, France

    Alexandra Rouquette

  7. Medical Diagnostic Discovery Department, BioMérieux SA, Lyon, France

    Virginie Moucadel

  8. Experimental Neuropathology Unit, Institut Pasteur, Paris, France

    Jean-Marc Cavaillon

  9. Service de Réanimation Médicale, Hôpital Charles Nicolle and Groupe de Recherche sur l’Adaptation Microbienne, Université de Rouen Normandie, EA 2656, Rouen, France

    Benoît Misset

Authors
  1. George Briassoulis
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Panagiotis Briassoulis
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Marianna Miliaraki
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Stavroula Ilia
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Marianna Parlato
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. François Philippart
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Alexandra Rouquette
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Virginie Moucadel
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Jean-Marc Cavaillon
    View author publications

    You can also search for this author in PubMed Google Scholar

  10. Benoît Misset
    View author publications

    You can also search for this author in PubMed Google Scholar

Consortia

Combined Approach for The eArly diagnosis of INfection in sepsis (CAPTAIN) study group

  • Sébastien Jacqmin
  • , Didier Journois
  • , Alix Lagrange
  • , Gabrielle Pinot de Villechenon
  • , Nadia Aissaoui
  • , Jean-Luc Diehl
  • , Emmanuel Guerot
  • , Marion Venot
  • , Olfa Hamzaoui
  • , Dominique Prat
  • , Benjamin Sztrymf
  • , Djillali Annane
  • , Virginie Maxime
  • , Andrea Polito
  • , Belaïd Bouhemad
  • , Cédric Bruel
  • , Frédéric Ethuin
  • , Julien Fournier
  • , Maïté Garrouste-Orgeas
  • , Charles Gregoire
  • , Nicolas Lau
  • , Benoît Misset
  • , François Philippart
  • , Jean-Pierre Bedos
  • , Pierrick Crosnier
  • , Virginie Laurent
  • , Sybille Merceron
  • , Elsa Bournaud
  • , Laurence Lecomte
  • , Jean-Marc Treluyer
  • , Alexandre Pachot
  • , Javier Yugueros-Marcos
  • , Laurent Esteve
  • , Sophie Blein,Virginie Moucadel
  • , Myriam Ben Boutieb
  • , Alexandra Rouquette
  • , Joël Coste
  • , Minou Adib-Conguy
  • , Jean-Marc Cavaillon
  • , Catherine Fitting
  • , Marianna Parlato
  • , Virginie Puchois
  •  & Fernando Souza-Fonseca Guimaraes

Corresponding author

Correspondence to George Briassoulis.

Ethics declarations

Conflicts of interest

The authors declare that they have no conflict of interest.

Additional information

The members of the Combined Approach for The eArly diagnosis of INfection in sepsis (CAPTAIN) study group were given in Acknowledgements section.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Briassoulis, G., Briassoulis, P., Miliaraki, M. et al. Biomarker cruises in sepsis: who is the CAPTAIN? Discussion on “Circulating biomarkers may be unable to detect infection at the early phase of sepsis in ICU patients: the CAPTAIN prospective multicenter cohort study”. Intensive Care Med 45, 132–133 (2019). https://doi.org/10.1007/s00134-018-5451-y

Download citation

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00134-018-5451-y

Search

Navigation