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  • Book
  • © 2012

Stem Cells and Cancer Stem Cells, Volume 6

Therapeutic Applications in Disease and Injury

Editors:

  1. M.A. Hayat

    1. , Kean University, Room 213, Library building, Union, USA

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  • Treatment of cancer patients
  • Methods for tissue engineering
  • Role of growth promoting factors in cancer
  • Treatment of injuries using cell therapy
  • Extensively illustrated with color figures

Part of the book series: Stem Cells and Cancer Stem Cells (STEM, volume 6)

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Table of contents (37 chapters)

  1. Front Matter

    Pages i-xxiii
    PDF

  2. Embryonic Stem Cells

    1. Front Matter

      Pages 1-1
      PDF

    2. Propagation of Human Embryonic Stem Cells: Role of TGF β

      • Prasad Pethe, Deepa Bhartiya
      Pages 3-9

    4. Gene Expression and Epigenetic Signatures of Germ Cell-Derived Pluripotent Stem Cells and Embryonic Stem Cells

      • Jessica Nolte, D. V. Krishna Pantakani, Hassan Dihazi, Ulrich Zechner
      Pages 21-34

    8. Differentiation of Embryonic Stem Cells into Cardiomyocytes: Role of Ouabain

      • Yee-Ki Lee, Kwong-Man Ng, Wing-Hon Lai, Yau-Chi Chan, Yee-Man Lau, Hung-Fat Tse et al.
      Pages 71-78

    9. Function of Myc for Generation of Induced Pluripotent Stem Cells

      • Masato Nakagawa, Shinya Yamanaka
      Pages 79-85

    10. Differentiation of Human Pluripotent Stem Cells into Retinal Cells

      • Masha Idelson, Benjamin Reubinoff
      Pages 87-99

  3. Mesenchymal Stem Cells

    1. Front Matter

      Pages 111-111
      PDF

    3. Molecular and Signaling Pathways That Modulate Mesenchymal Stem Cell Self-renewal

      • Sarika Saraswati, Dikshya Bastakoty, Pampee P. Young
      Pages 131-141

    4. The Biology and Regenerative Potential of Stem Cells and Their Mesenchymal Progeny

      • Markus Neubauer, Heike Wegmeyer, Ralf Huss
      Pages 143-160

    5. Mesenchymal Stem Cells: Clinical Applications (An Overview)

      • Aaron Liew, Timothy O’Brien
      Pages 161-175

    6. Mesenchymal Stem Cells for the Treatment of Cancer

      • Manuel Ramírez, Javier García Castro
      Pages 177-183

    8. Utility of Mesenchymal Stem Cell Therapy in Type 1 Diabetes

      • Robert F. Moore, Marwan Mounayar, Reza Abdi
      Pages 197-203
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About this book

The difference among pluripotent stem cells, multipotent stem cells, and unipotent stem cells is pointed out. Vast therapeutic applications of the following specific stem cells in disease and tissue injury are discussed: human embryonic stem cells, human mesenchymal stem cells, germ cell-derived pluripotent stem cells, induced pluripotent stem cells, human umbilical cord blood-derived stem cells, breast tumor stem cells,and hematopoietic stem cells. Because of the potential of human embryonic stem cells to produce unlimited quantities of any human cell type, considerable focus is placed on their therapeutic potential. Because of their pluripotency, these cells have been used in various applications such as tissue engineering, regenerative medicine, pharmacological and toxicological studies, and fundamental studies of cell differentiation. The formation of embryoid bodies, which are three-dimensional aggregates of embryonic stem cells, is explained as this is the first step in cell differentiation. Such embryoid body culture has been widely used as a trigger for the in vitro differentiation of embryonic stem cells. The basic capacity of self-renewal of human embryogenic stem cells is explained. The role of TGF-beta in the propagation of human embryonic stem cells is discussed. The differentiation of human embryonic stem cells into neurons, hepatocytes, cardiomyocytes, and retinal cells is fully explained. Donor policies for hematopoietic stem cells are also explained.
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Keywords

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Editors and Affiliations

  • , Kean University, Room 213, Library building, Union, USA

    M.A. Hayat

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Bibliographic Information

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Access via your institution

Buy it now

eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

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