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Interictal EEG

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Atlas of Epilepsies

Concept and Definition

The diagnosis of epilepsy is primarily clinical; however, routine interictal EEG plays a crucial role in the diagnosis and management of patients with this paroxysmal neurological disorder (Binnie and Stefan 1999; Pillai and Sperling 2006).

Interictal EEG is defined as an electroencephalographic recording that does not contain seizures or ictal manifestations and is therefore obtained in the intervals between clinical attacks. It is the most frequent recording type in the clinical practice.

Utility of the Interictal EEG

Routine EEG is generally performed for detecting interictal epileptiform activity (IEA) such as spikes, polyspikes, sharp waves, spike-and-wave, and sharp-and-slow wave complexes. The presence of IEA in a mental and neurologically normal subject, in an appropriate clinical context, has a high positive predictive value for the diagnosis of epilepsy (Pedley et al. 2003). However, its presence should be considered with precaution in subjects with...

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Abbreviations

IEA:

Interictal epileptiform activity

IEDs:

Interictal epileptiform discharges

IGEs:

Idiopathic generalized epilepsies

IPS:

Intermittent photic stimulation

OPM:

Orbitofrontal photomyoclonus

PLEDs:

Periodic lateralized epileptiform discharges

SREDA:

Subclinical rhythmic electrographic discharges in adults

References

  • Alarcón G, Binnie CD, García Seoane JJ, Martín Miguel C, Fernández-Torre JL, Polkey CE, Guy CN (1999) Mechanisms involved in the propagation of interictal activity in partial epilepsy. In: Comi G, Lüking CH, Kimura J, Rossini P (eds) Clinical neurophysiology: from receptors to perception, EEG Suppl. 50.Elsevier Science BV, Amsterdam, pp 259–278

    Google Scholar 

  • Aliberti V, Grunewald RA, Panayiotopoulos CP, Chroni E (1994) Focal electroencephalographic abnormalities in juvenile myoclonic epilepsy. Epilepsia 35:297–301

    Article  CAS  PubMed  Google Scholar 

  • Binnie CD, Prior PF (1994) Electroencephalography. J Neurol Neurosurg Psychiatry 57:1308–1319

    Article  CAS  PubMed  Google Scholar 

  • Binnie CD, Stefan H (1999) Modern electroencephalography: its role in epilepsy management. Clin Neurophysiol 110:1671–1697

    Article  CAS  PubMed  Google Scholar 

  • Binnie CD, Stefan H (2003) The EEG in epilepsy. In: Binnie C, Cooper R, Mauguière F, Osselton J, Prior P, Tedman B (eds) Clinical neurophysiology, vol 2. EEG, paediatric neurophysiology, special techniques and applications, 1st edn. Elsevier Science BV, Amsterdam, pp 268–306

    Google Scholar 

  • Kasteleijn-Nolst-Trenité DGA, Binnie CD, Harding GFA, Wilkins A (1999) Photic stimulation: standardization of screening methods. Epilepsia 40(4):75–79

    Article  PubMed  Google Scholar 

  • Koutroumanidis M, Smith S (2005) Use and abuse of EEG in the diagnosis of Idiopathic generalized epilepsies. Epilepsia 46(9):96–107

    Article  PubMed  Google Scholar 

  • Markand O (2003) Pearls, perils, and pitfalls in the use of the electroencephalogram. Semin Neurol 23:7–46

    Article  PubMed  Google Scholar 

  • Mendez OE, Brenner RP (2006) Increasing the yield of EEG. J Clin Neurophysiol 23:282–293

    Article  PubMed  Google Scholar 

  • Panayiotopoulos CP (2007) A clinical guide to epileptic syndromes and their treatment. Springer, London

    Google Scholar 

  • Panayiotopoulos CP, Chroni E, Daskalopoulos C, Baker A, Rowlinson S, Walsh P (1992) Typical absence seizures in adults: clinical, EEG, video-EEG findings and diagnostic/syndromic considerations. J Neurol Neurosurg Psychiatry 55:1002–1008

    Article  CAS  PubMed  Google Scholar 

  • Pedley TA, Mendiratta A, Walczack TS (2003) Seizures and epilepsy. In: Ebersole JS, Pedley TA (eds) Current practice of clinical electroencephalography, 3rd edn. Lippincott Williams & Wilkins, New York, pp 506–587

    Google Scholar 

  • Pillai J, Sperling MR (2006) Interictal EEG and the diagnosis of epilepsy. Epilepsia 47(1):14–22

    Article  PubMed  Google Scholar 

  • Smith SJM (2005) EEG in the diagnosis, classification, and management of patients with epilepsy. J Neurol Neurosurg Psychiatry 76(2):ii2–ii17

    Article  PubMed  Google Scholar 

  • Tatum WO, Husain AM, Benbadis SR, Kaplan PW (2006) Normal adult EEG and patterns of uncertain significance. J Clin Neurophysiol 23:194–207

    Article  PubMed  Google Scholar 

  • Westmoreland B (2003) Benign epilepto-encephalographic variants and patterns of uncertain clinical significance. In: Ebersole JS, Pedley TA (eds) Current practice of clinical electroencephalography, 3rd edn. Lippincott Williams & Wilkins, New York, pp 235–245

    Google Scholar 

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Fernández-Torre, J.L. (2010). Interictal EEG. In: Panayiotopoulos, C.P. (eds) Atlas of Epilepsies. Springer, London. https://doi.org/10.1007/978-1-84882-128-6_101

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  • DOI: https://doi.org/10.1007/978-1-84882-128-6_101

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-84882-127-9

  • Online ISBN: 978-1-84882-128-6

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