Abstract
Both chemists and biologists have been intrigued for many years by the role of secondary metabolites in plants of terrestrial and marine origins. Of equal interest is whether such compounds have antitumor, antiviral, or antimutagenic properties. For example, the highly active antitumor agents, camptothecin and taxol, have been isolated from the bark and wood of trees (13,21), and another active agent, bryostatin I, from a marine animal (11). Dudley Williams has proposed that “secondary metabolites are a measure of the fitness of the organism to survive by repelling or entrapping other organisms” (23). Mitscher has stated that “as some constituents of higher plants are mutagens, it seems reasonable that substances capable of antimutagenicity also be produced by such plants” (10).
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Wall, M.E., Wani, M.C. (1993). Antimutagenic Agents from Natural Products of Terrestrial and Marine Origin. In: Bronzetti, G., Hayatsu, H., De Flora, S., Waters, M.D., Shankel, D.M. (eds) Antimutagenesis and Anticarcinogenesis Mechanisms III. Basic Life Sciences, vol 61. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2984-2_7
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DOI: https://doi.org/10.1007/978-1-4615-2984-2_7
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