Virion
Morphology: |
Icosahedral, triple-layered |
Envelope: |
No |
Diameter (nm): |
75 |
Length (nm): |
– |
Structural components: |
VP2, VP1 and VP3, VP6, VP4 and VP7 |
Buoyant density (g/mL): |
1.36–1.38 |
Buoyant density method: |
CsCl gradient |
Lipid composition: |
Not applicable |
Additional information: |
VP4 (spike-like trimer) interacts with VP7 and VP6; triangulation number T = 13 of double shell; 132 channels penetrating both shells (120 channels along the 6-coordinated centers and 12 along the fivefold symmetry axis) |
Genome
Nucleic acid: |
RNA |
|
Strandedness: |
Double-stranded |
|
Polarity: |
Positive or negative-sense |
|
Configuration: |
Linear |
|
Segment organization: |
Segment no. 1 (kb): |
3.3 |
Segment no. 2 (kb): |
2.6 |
|
Segment no. 3 (kb): |
2.6 |
|
Segment no. 4 (kb): |
2.4 |
|
Segment no. 5 (kb): |
1.6 |
|
Segment no. 6 (kb): |
1.4 |
|
Segment no. 7 (kb): |
1.1 |
|
Segment no. 8 (kb): |
1.1 |
|
Segment no. 9 (kb): |
1.1 |
|
Segment no. 10 (kb): |
0.7 |
|
Segment no. 11 (kb): |
0.7 |
|
11 segment(s): |
18.6 (kb) total (calculated) |
|
G + C content (%): |
33–42 |
|
mRNA transcripts: |
12 |
|
Open... |
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Advisory Committee on Immunization Practices (ACIP) (1999) Rotavirus vaccine for the prevention of rotavirus gastroenteritis among children. Recommendations of the ACIP. Morb Mort Wkly Rep 48(RR-2):1–23
Desselberger U (1996) Genome rearrangements in rotaviruses. Adv Virus Res 46:69–95
Desselberger U (1998a) Reoviruses. In: Mahy BWJ, Collier L (eds) Topley and Wilson’s microbiology and microbial infections, ninth edition, volume 1: virology. E Arnold, London, pp 537–550
Desselberger U (1998b) Prospects for vaccines against rotaviruses. Rev Med Virol 8:43–52
Desselberger U (1999) Rotavirus infection: guidelines for treatment and prevention. Drugs 58:447–452
Desselberger U (2000) Viruses associated with acute diarrhoeal disease. In: Zuckerman A, Banatvala J, Pattison J (eds) Principles and practice of clinical virology, 4th edn. Wiley, Chichester, p 253
Desselberger U, Gray J (2009) Rotaviruses. In: Zuckerman AJ, Banatvala JE, Schoub BD, Griffiths PD, Mortime P (eds) Principles and Practice of Clinical Virology. Wiley & Blackwell, Chichester, pp 337–353
Desselberger U, Gray J, Estes MK (2005) Rotaviruses. In: Topley and Wilson’s microbiology & microbial infections, 10th edn. Hodder Arnold, London, pp 946–958
Estes MK, Kapikian AZ et al (2007) Rotaviruses. In: Knipe DM, Howley PM (eds) Fields virology, 5th edn. Wolters Kluwer Health/Lippincott Williams & Wilkins, Philadelphia, pp 1917–1974
Gray JJ, Desselberger U (eds) (2000) Rotaviruses: methods in molecular medicine. Humana Press, Totowa, p 262
Kapikian AZ, Chanock RM (1996) Rotaviruses. In: Fields BN, Knipe DM, Howley PM et al (eds) Fields Virology, 3rd edn. Lippincott-Raven, Philadelphia, pp 1657–1708
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2011 Springer Science+Business Media, LLC
About this entry
Cite this entry
Desselberger, U., Gray, J.J. (2011). Rotavirus. In: Tidona, C., Darai, G. (eds) The Springer Index of Viruses. Springer, New York, NY. https://doi.org/10.1007/978-0-387-95919-1_267
Download citation
DOI: https://doi.org/10.1007/978-0-387-95919-1_267
Publisher Name: Springer, New York, NY
Print ISBN: 978-0-387-95918-4
Online ISBN: 978-0-387-95919-1
eBook Packages: Biomedical and Life SciencesReference Module Biomedical and Life Sciences