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Rotavirus

Reoviridae

  • Reference work entry
The Springer Index of Viruses

Virion

Morphology:

Icosahedral, triple-layered

Envelope:

No

Diameter (nm):

75

Length (nm):

–

Structural components:

VP2, VP1 and VP3, VP6, VP4 and VP7

Buoyant density (g/mL):

1.36–1.38

Buoyant density method:

CsCl gradient

Lipid composition:

Not applicable

Additional information:

VP4 (spike-like trimer) interacts with VP7 and VP6; triangulation number T = 13 of double shell; 132 channels penetrating both shells (120 channels along the 6-coordinated centers and 12 along the fivefold symmetry axis)

Genome

Nucleic acid:

RNA

Strandedness:

Double-stranded

Polarity:

Positive or negative-sense

Configuration:

Linear

Segment organization:

Segment no. 1 (kb):

3.3

Segment no. 2 (kb):

2.6

Segment no. 3 (kb):

2.6

Segment no. 4 (kb):

2.4

Segment no. 5 (kb):

1.6

Segment no. 6 (kb):

1.4

Segment no. 7 (kb):

1.1

Segment no. 8 (kb):

1.1

Segment no. 9 (kb):

1.1

Segment no. 10 (kb):

0.7

Segment no. 11 (kb):

0.7

11 segment(s):

18.6 (kb) total (calculated)

G + C content (%):

33–42

mRNA transcripts:

12

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References

  • Advisory Committee on Immunization Practices (ACIP) (1999) Rotavirus vaccine for the prevention of rotavirus gastroenteritis among children. Recommendations of the ACIP. Morb Mort Wkly Rep 48(RR-2):1–23

    Google Scholar 

  • Desselberger U (1996) Genome rearrangements in rotaviruses. Adv Virus Res 46:69–95

    Article  PubMed  CAS  Google Scholar 

  • Desselberger U (1998a) Reoviruses. In: Mahy BWJ, Collier L (eds) Topley and Wilson’s microbiology and microbial infections, ninth edition, volume 1: virology. E Arnold, London, pp 537–550

    Google Scholar 

  • Desselberger U (1998b) Prospects for vaccines against rotaviruses. Rev Med Virol 8:43–52

    Article  PubMed  CAS  Google Scholar 

  • Desselberger U (1999) Rotavirus infection: guidelines for treatment and prevention. Drugs 58:447–452

    Article  PubMed  CAS  Google Scholar 

  • Desselberger U (2000) Viruses associated with acute diarrhoeal disease. In: Zuckerman A, Banatvala J, Pattison J (eds) Principles and practice of clinical virology, 4th edn. Wiley, Chichester, p 253

    Google Scholar 

  • Desselberger U, Gray J (2009) Rotaviruses. In: Zuckerman AJ, Banatvala JE, Schoub BD, Griffiths PD, Mortime P (eds) Principles and Practice of Clinical Virology. Wiley & Blackwell, Chichester, pp 337–353

    Chapter  Google Scholar 

  • Desselberger U, Gray J, Estes MK (2005) Rotaviruses. In: Topley and Wilson’s microbiology & microbial infections, 10th edn. Hodder Arnold, London, pp 946–958

    Google Scholar 

  • Estes MK, Kapikian AZ et al (2007) Rotaviruses. In: Knipe DM, Howley PM (eds) Fields virology, 5th edn. Wolters Kluwer Health/Lippincott Williams & Wilkins, Philadelphia, pp 1917–1974

    Google Scholar 

  • Gray JJ, Desselberger U (eds) (2000) Rotaviruses: methods in molecular medicine. Humana Press, Totowa, p 262

    Google Scholar 

  • Kapikian AZ, Chanock RM (1996) Rotaviruses. In: Fields BN, Knipe DM, Howley PM et al (eds) Fields Virology, 3rd edn. Lippincott-Raven, Philadelphia, pp 1657–1708

    Google Scholar 

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Correspondence to Ulrich Desselberger M.D., FRCPath, FRCP .

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Desselberger, U., Gray, J.J. (2011). Rotavirus. In: Tidona, C., Darai, G. (eds) The Springer Index of Viruses. Springer, New York, NY. https://doi.org/10.1007/978-0-387-95919-1_267

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