8 Result(s)

within Jacob Tfelt-Hansen

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  1. No Access


    Pharmacokinetic Variability of Drugs Used for Prophylactic Treatment of Migraine

    In this review, we evaluate the variability in the pharmacokinetics of 11 drugs with established prophylactic effects in migraine to facilitate ‘personalized medicine’ with these drugs. PubMed was searched for...

    Peer Tfelt-Hansen, Frederik Nybye Ågesen, Agniezka Pavbro, Jacob Tfelt-Hansen in CNS Drugs (2017)

  2. Article

    Pharmacological blockade of small conductance Ca2+-activated K+ channels by ICA reduces arrhythmic load in rats with acute myocardial infarction

    Acute myocardial infarction (AMI) with development of ventricular fibrillation (VF) is a common cause of sudden cardiac death (SCD). At present, no pharmacological treatment has successfully been able to preve...

    Laura A. Hundahl, Stefan M. Sattler in Pflügers Archiv - European Journal of Phys… (2017)

  3. Open Access This content is freely available online to anyone, anywhere at any time.


    Gender differences in sudden cardiac death in the young-a nationwide study

    Hitherto, sudden cardiac death (SCD) in the young has been described with no distinction between genders. SCD occurs more often in men (SCDm) than women (SCDw), but this disparity is not understood and has not...

    Bo Gregers Winkel, Bjarke Risgaard, Thea Bjune in BMC Cardiovascular Disorders (2017)

  4. Chapter and Conference Paper

    From CMR Image to Patient-Specific Simulation and Population-Based Analysis: Tutorial for an Openly Available Image-Processing Pipeline

    Cardiac magnetic resonance (CMR) imaging is becoming a routine diagnostic and therapy planning tool for some cardiovascular diseases. It is still challenging to properly analyse the acquired data, and the curr...

    Maciej Marciniak, Hermenegild Arevalo in Statistical Atlases and Computational Mode… (2017)

  5. Open Access This content is freely available online to anyone, anywhere at any time.


    Sudden death in young persons with uncontrolled asthma - a nationwide cohort study in Denmark

    Asthma is a common chronic disease among young adults, and several studies have reported increased mortality rates in patients with asthma. However, no study has described sudden unexpected death in a nationwi...

    Anders Juul Gullach, Bjarke Risgaard, Thomas Hadberg Lynge in BMC Pulmonary Medicine (2015)

  6. Open Access This content is freely available online to anyone, anywhere at any time.


    New population-based exome data question the pathogenicity of some genetic variants previously associated with Marfan syndrome

    Marfan syndrome (MFS) is a rare autosomal dominantly inherited connective tissue disorder with an estimated prevalence of 1:5,000. More than 1000 variants have been previously reported to be associated with MF...

    Ren-Qiang Yang, Javad Jabbari, Xiao-Shu Cheng, Reza Jabbari in BMC Genetics (2014)

  7. Article

    Differences in investigations of sudden unexpected deaths in young people in a nationwide setting

    Inherited disease may be causative in many young sudden unexpected death cases. Autopsy is essential in the counselling of the bereaved, as the family of the victim may be at risk too. In a nationwide setting ...

    Bo Gregers Winkel, Anders Gaarsdal Holst in International Journal of Legal Medicine (2012)

  8. Open Access This content is freely available online to anyone, anywhere at any time.


    Whole-genome amplified DNA from stored dried blood spots is reliable in high resolution melting curve and sequencing analysis

    The use of dried blood spots (DBS) samples in genomic workup has been limited by the relative low amounts of genomic DNA (gDNA) they contain. It remains to be proven that whole genome amplified DNA (wgaDNA) fr...

    Bo G Winkel, Mads V Hollegaard, Morten S Olesen, Jesper H Svendsen in BMC Medical Genetics (2011)