Synonyms
Expansion of Targeted Hydrophobic Compounds Using a Modifier
As previously described, SC–CO2 is a suitable medium to extract hydrophobic compounds. On the other hand, complex lipids (e.g., phospholipids, PLs, and glycolipids, GLs) have higher polarity than neutral lipids (e.g., TAG), because they have a hydrophilic head groups (i.e., phosphate groups or sugars). Therefore, extraction efficiencies of complex lipids are lower than that of neutral lipids by SFE with SC–CO2. However, the polarity of SC–CO2can be changed considerably by adding a polar organic solvent such as methanol, ethanol, etc., as a modifier. Thus, in recent years, many SFE applications using greener and less toxic...
Keywords
- Supercritical Fluid Chromatography-mass Spectrometry
- Dried Plasma Spots
- Complex Lipid Extracts
- Liquid Extraction
- Newborn Mass Screening
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Takeda, H., Izumi, Y., Bamba, T. (2016). Supercritical Fluid Extraction: Modifier. In: Wenk, M. (eds) Encyclopedia of Lipidomics. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-7864-1_101-1
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DOI: https://doi.org/10.1007/978-94-007-7864-1_101-1
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