Skip to main content

Urtikaria und Angioödem

  • Living reference work entry
  • First Online:

Part of the book series: Springer Reference Medizin ((SRM))

Zusammenfassung

Urtikaria und Angioödem sind sehr häufige Symptome. Ihre Zuordnung zu einem Krankheitsbild entsprechend der aktuellen Nomenklatur/Klassifikation ist meist unproblematisch. Bei den meist für viele Jahre persistierenden chronischen Formen dagegen stellen Ursachensuche, Management und die adäquate Therapie eine Herausforderung für den Behandler dar.

This is a preview of subscription content, log in via an institution.

Literatur

  • Beck LA, Bernstein JA, Maurer M (2017) A review of international recommendations for the riagnosis and management of chronic crticaria. Acta Derm Venereol 97:149–158. doi:10.2340/00015555-2496 [Epub vor Druck]

    Article  PubMed  Google Scholar 

  • Bork K (2016) A decade of change: recent developments in pharmacotherapy of hereditary angioedema (HAE). Clin Rev Allergy Immunol 51:183–192

    Article  CAS  PubMed  Google Scholar 

  • Bork K, Maurer M, Bas M et al (2012) Hereditäres Angioödem durch C1-Inhibitor-Mangel. AWMF-Leitlinie. Allergo J 21:109–120

    Article  Google Scholar 

  • Boyden SE, Desai A, Cruse G et al (2016) Vibratory urticaria associated with a missense variant in ADGRE2. N Engl J Med 374:656–663

    Google Scholar 

  • Brodell LA, Beck LA, Saini SS (2008) Pathophysiology of chronic urticaria. Ann Allergy Asthma Immunol 100:291–297

    Article  CAS  PubMed  Google Scholar 

  • Cicardi M, Aberer W, Banerji A et al (2014) Classification, diagnosis, and approach to treatment for angioedema: consensus report from the hereditary angioedema international working group. HAWK under the patronage of EAACI (European academy of allergy and clinical immunology). Allergy 69:602–616

    Article  CAS  PubMed  Google Scholar 

  • Church MK, Maurer M, Simons FE et al (2010) Risk of first-generation H(1)-antihistamines: a GA(2)LEN position paper. Allergy 65:459–466

    Article  CAS  PubMed  Google Scholar 

  • Farkas H, Martinez-Saguer I, Bork K et al (2017) International consensus on the diagnosis and management of pediatric patients with hereditary angioedema with C1-Inhibitor deficiency. Allergy. doi:10.1111/all.13001 [Epub vor Druck]

    PubMed  Google Scholar 

  • Guillèn-Aguinaga S, Jáuregui Presa I, Aguinaga-Ontoso E et al (2017) Up-dosing non-sedating antihistamines in patients with chronic spontaneous urticaria: a systematic review and meta-analysis. Br J Dermatol 175:1153–1165

    Article  Google Scholar 

  • Kaplan A, Ferrer M, Bernstein JA et al (2016) Timing and duration of omalizumab response in patients with chronic idiopathic/spontaneous urticaria. J Allergy Clin Immunol 137:474–481

    Article  CAS  PubMed  Google Scholar 

  • Konstantinou GN, Asero R, Maurer M et al (2009) EAACI/GA(2)LEN task force consensus report: the autologous serum skin test in urticaria. Allergy 64:1256–1268

    Article  CAS  PubMed  Google Scholar 

  • Krause K, Grattan CE, Bindslev-Jensen C et al (2012) How not to miss autoinflammatory diseases masquerading as urticaria. Allergy 67:1465–1474

    Article  CAS  PubMed  Google Scholar 

  • Magerl M, Altrichter S, Borzova E et al (2016) The definition, diagnostic testing, and management of chronic inducible urticarias – the EAACI/GA(2) LEN/EDF/UNEV consensus recommendations 2016 update and revision. Allergy 71:780–802

    Article  CAS  PubMed  Google Scholar 

  • Maurer M, Rosen K, Hsieh HJ et al (2013) Omalizumab for the treatment of chronic idiopathic or spontaneous urticaria. N Engl J Med 368:924–935

    Article  CAS  PubMed  Google Scholar 

  • Pite H, Wedi B, Borrego LM et al (2013) Management of childhood urticaria: current knowledge and practical recommendations. Acta Derm Venereol 93:500–508

    Article  PubMed  Google Scholar 

  • Potter PC, Kapp A, Maurer M et al (2009) Comparison of the efficacy of levocetirizine 5 mg and desloratadine 5 mg in chronic idiopathic urticaria patients. Allergy 64:596–604

    Article  CAS  PubMed  Google Scholar 

  • Reese I, Zuberbier T, Bunselmeyer B et al (2009) Diagnostisches Vorgehen bei Verdacht auf eine Pseudoallergische Reaktion auf Nahrungsmittelzusatzstoffe. J Dtsch Dermatol Ges 7:70–77

    PubMed  Google Scholar 

  • Sabroe RA, Greaves MW (2006) Chronic idiopathic urticaria with functional autoantibodies: 12 years on. Br J Dermatol 154:813–819

    Article  CAS  PubMed  Google Scholar 

  • Staevska M, Gugutkova M, Lazarova C et al (2014) Night-time sedating H1-antihistamine increases daytime somnolence but not treatment efficacy in chronic spontaneous urticaria: a randomized controlled trial. Br J Dermatol 171:148–154

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Wedi B (2010) Therapy of urticaria. In: Zuberbier T, Grattan C, Maurer M (Hrsg) Urticaria and angioedema. Springer, Berlin, S 129–139

    Chapter  Google Scholar 

  • Wedi B (2015) Successful treatment of the different urticaria subtypes. Curr Dermatol Rep 4:71–76

    Article  Google Scholar 

  • Wedi B, Kapp A (2016) Urticaria and angioedema. In: Mahmoudi M (Hrsg) Allergy and asthma: practical diagnosis and management. Springer International, Switzerland, S 143–165

    Chapter  Google Scholar 

  • Wedi B, Raap U, Wieczorek D et al (2009) Urticaria and infections. Allergy Asthma Clin Immunol 5:10

    Article  PubMed  PubMed Central  Google Scholar 

  • Wedi B, Wieczorek D, Raap U, Kapp A (2013) Urtikaria … und die Therapie versagt. Hautarzt 64:656–663

    Article  CAS  PubMed  Google Scholar 

  • Wedi B, Wieczorek D, Raap U et al (2014) Urticaria. J Dtsch Dermatol Ges 12:997–1007

    PubMed  Google Scholar 

  • Weller K, Peveling-Oberhag A, Altrichter S et al (2016) Instruments for the determination of disease activity, disease control, and impairment of quality of life in patients with chronic urticaria and angioedema. Allergologie 39:6–15

    Article  Google Scholar 

  • Wieczorek D, Langhorst J, Kapp A, Wedi B (2013) Urtikaria. Manchmal doch IgE-vermittelt? Hautarzt 64:644–649

    Article  CAS  PubMed  Google Scholar 

  • Wieczorek D, Kapp A, Wedi B (2016) Omalizumab in Urticaria: one for all? Allergologie 39:22–28

    Article  Google Scholar 

  • Zhao ZT, Ji CM, Yu WJ et al (2016) Omalizumab for the treatment of chronic spontaneous urticaria: a meta-analysis of randomized clinical trials. J Allergy Clin Immunol 137:1742–1750

    Article  CAS  PubMed  Google Scholar 

  • Zuberbier T, Grattan C, Maurer M (Hrsg) (2010a) Urticaria and angioedema. Springer, Berlin

    Google Scholar 

  • Zuberbier T, Balke M, Worm M et al (2010b) Epidemiology of urticaria: a representative cross-sectional population survey. Clin Exp Dermatol 35:869–873

    Article  CAS  PubMed  Google Scholar 

  • Zuberbier T, Aberer W, Asero R et al (2014) EAACI/GA(2)LEN/EDF/WAO guideline forthe definition, classification, diagnosis and management of urticaria. The 2013 revision and update. Allergy 69:868–887

    Article  CAS  PubMed  Google Scholar 

Erstbeschreiber

  • Alsenz J, Bork K, Loos M (1987) Autoantibody-mediated acquired deficiency of C1 inhibitor. N Engl J Med 316:1360–1366

    Article  CAS  PubMed  Google Scholar 

  • Bork K, Barnstedt SE, Koch P et al (2000) Hereditary angioedema with normal C1-inhibitor activity in women. Lancet 356:213–217

    Article  CAS  PubMed  Google Scholar 

  • Bovet D, Staub A (1937) Action protectrice des éthers phenoliques au cours de l’intoxication histaminique. C R Soc Biol 124:547

    CAS  Google Scholar 

  • Boyden SE, Desai A, Cruse G et al (2016) Vibratory urticaria associated with a missense variant in ADGRE2. N Engl J Med 374:656–663

    Google Scholar 

  • Caldwell JR, Ruddy S, Schur PH et al (1972) Acquired C1 inhibitor deficiency in lymphosarcoma. Clin Immunol Immunopathol 1:39–52

    Article  Google Scholar 

  • Cullen W (1769) Synopsis nosologiae methodicae. Pars quatra, Edinburgi

    Google Scholar 

  • Dale HH, Laidlow PP (1910) The physiological action of imidiazolethylamine. J Physiol (Lond) 41:318

    Article  CAS  Google Scholar 

  • Dewald G, Bork K (2006) Missense mutations in the coagulation factor XII (Hageman factor) gene in hereditary angioedema with normal C1 inhibitor. Biochem Biophys Res Commun 343:1286–1289

    Article  CAS  PubMed  Google Scholar 

  • Dinkelacker E (1882) Ueber acutes Oedem. Medizinische Dissertation, Universität Kiel, Mohr Kiel

    Google Scholar 

  • Donaldson VH, Evans RR (1963) A biochemical abnormality in hereditary angioneurotic edema: absence of serum inhibitor of C1-esterase. Am J Med 35:37–44

    Article  CAS  PubMed  Google Scholar 

  • Donati M (1586) De medica historica mirabilis, Bd 6. Osana, Mantuae

    Google Scholar 

  • Duke WW (1924) Urticaria caused specifically by the action of physical agents. JAMA 83:3–9

    Article  Google Scholar 

  • Gell PGH, Coombs RRA (1963) The classification of allergic reactions underlying disease. In: Coombs RRA, Gell PGH (Hrsg) Clinical aspects of immunology. Blackwell, Oxford

    Google Scholar 

  • Gleich GJ, Schroeter AL, Marcoux P et al (1984) Episodic angioedema associated with eosinophilia. N Engl J Med 310:1621–1626

    Article  CAS  PubMed  Google Scholar 

  • Hjorth N, Roed-Petersen J (1975) Berufsekzeme durch Proteine. Z Hautkr 50:851–852

    CAS  PubMed  Google Scholar 

  • Kern F, Lichtenstein LM (1976) Defective histamine release in chronic urticaria. J Clin Invest 57:1369–1377

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Kossard S, Hamann I, Wilkinson B (2006) Defining urticarial dermatitis: a subset of dermal hypersensitivity reaction pattern. Arch Dermatol 142:29–34

    PubMed  Google Scholar 

  • Lewis ST (1927) The blood vessels of the human skin and their responses. Shaw, London

    Google Scholar 

  • Milton JL (1876–1877) On giant urticaria. Edinb Med J 22:513–526

    Google Scholar 

  • Osler W (1888) Hereditary angio-neurotic oedema. Am J Med Sci 95:362–367

    Article  Google Scholar 

  • Patterson R, Mellies CJ, Blankenship ML, Pruzansky JJ (1972) Vibratory angioedema: a hereditary type of physical hypersensitivity. J Allergy Clin Immunol 50:174–182

    Article  CAS  PubMed  Google Scholar 

  • Quincke HI (1882) Ueber akutes umschriebenes Hautodem. Monatsheft Prakt Dermatol 1:129–131

    Google Scholar 

  • Shelley WB, Rawnsley HM (1964) Aquagenic urticaria. Contact hypersensitivity to water. JAMA 189:895–898

    CAS  PubMed  Google Scholar 

  • Shelley WB, Shelley ED (1985) Adrenergic urticaria: a new form of stressinduced hives. Lancet ii:1031–1033

    Article  Google Scholar 

  • Weber G, Braun-Falco O (1956) Zum Entstehungsmechanismus urtikarieller Röntgenreaktionen. Dermatol Wochenschr 134:892–895

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Bettina Wedi .

Editor information

Editors and Affiliations

Section Editor information

Rights and permissions

Reprints and permissions

Copyright information

© 2016 © Springer-Verlag GmbH Deutschland

About this entry

Cite this entry

Wedi, B. (2016). Urtikaria und Angioödem. In: Plewig, G., Ruzicka, T., Kaufmann, R., Hertl, M. (eds) Braun-Falco's Dermatologie, Venerologie und Allergologie. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-49546-9_29-2

Download citation

  • DOI: https://doi.org/10.1007/978-3-662-49546-9_29-2

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-49546-9

  • Online ISBN: 978-3-662-49546-9

  • eBook Packages: Springer Referenz Medizin

Publish with us

Policies and ethics