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Zöliakie/Einheimische Sprue

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DGIM Innere Medizin

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Zusammenfassung

Neue Erkenntnisse zur Pathogenese haben in den letzten Jahren zum verbesserten Verständnis von Epidemiologie, Diagnostik und Therapie der glutensensitiven Erkrankungen beigetragen. Die Zöliakie ist eine Erkrankung, die durch charakteristische morphologische Veränderungen der Dünndarmschleimhaut gekennzeichnet ist. Die Veränderungen sind Folge einer Empfindlichkeit gegenüber dem Glutenbestandteil Gliadin, das in verschiedenen Getreidesorten enthalten ist. Häufig bilden sich nach Glutenkarenz die Veränderungen am Dünndarm und die assoziierten klinischen Beschwerdebilder, die sehr unterschiedlich ausgeprägt sein können, zurück. In einigen Fällen treten jedoch therapierefraktäre Verläufe oder Komplikationen auf. Die im deutschen Sprachraum bislang oft (einheimische) Sprue genannte Erkrankung sollte im Hinblick auf eine international einheitliche Sprachregelung als Zöliakie bezeichnet werden. Man geht davon aus, dass das klassische Krankheitsbild der Zöliakie deutlich seltener ist als nichtklassische Verlaufsformen.

Die Originalversion dieses Kapitels wurde revidiert: Der Korrespondenzautor wurde geändert.

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Authors and Affiliations

  1. Abteilung Innere Medizin, Krankenhaus Maria-Hilf, Maria-Hilf-Str. 2, 54550, Daun, Deutschland

    Katja Eggeling & Thomas Marth

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  1. Katja Eggeling
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  2. Thomas Marth
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Correspondence to Thomas Marth .

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Editors and Affiliations

  1. Medizinische Klinik I, Universitätsklinikum Schleswig-Hoslstein, Campus Lübeck, Lübeck, Schleswig-Holstein, Germany

    Hendrik Lehnert

  2. TU Dresden Universitätsklinikum Carl Gustav Carus, Dresden, Germany

    Sebastian M. Schellong

  3. FB Gastroenterologie und Hepatologie, Universitätsklinikum Leipzig Medizinische Klinik und Poliklinik II, Leipzig, Sachsen, Germany

    Joachim Mössner

  4. Krankenhaus Barmherzige Brüder, Regensburg, Germany

    Cornel C. Sieber

  5. Nürnberg, Bayern, Germany

    Walter Swoboda

  6. Universitätsklinikum Giessen und Marburg Klinik für Innere Medizin, Marburg, Hessen, Germany

    Andreas Neubauer

  7. Interdisziplinärer Schwerpunkt für Hämos, Universitätsklinikum Gießen und Marburg, Gießen, Germany

    Bettina Kemkes-Matthes

  8. Klinik für Gastroenterologie,Hepatologie, Medizinische Hochschule Hannover, Hannover, Germany

    Michael P. Manns

  9. Sektion für Molekulare und Klinische Inf, Universitätsklinikum Schleswig-Holstein,, Lübeck, Germany

    Jan Rupp

  10. Abt. Kardiologie und Pneumologie, Universitätsklinikum Göttingen Herzzentrum Göttingen, Göttingen, Germany

    Gerd Hasenfuß

  11. Abt. Nephrologie und Klinische Immunologie, Univ.Klinikum Aachen Medizinische Klinik II, Aachen, Germany

    J. Floege

  12. Universitätsklinikum Köln Klinik I für Innere Medizin, Köln, Germany

    Michael Hallek

  13. Klinik für Pneumologie, Medizinische Hochschule Hannover (MHH) Zentrum Innere Medizin, Hannover, Germany

    Tobias Welte

  14. Klinik u. Poliklinik für Innere Medizin, Universitätsmedizin Greifswald, Greifswald, Germany

    Markus Lerch

  15. Dr.-Horst-Schmidt-Kliniken GmbH, Wiesbaden, Germany

    Elisabeth Märker-Hermann

  16. Klinische Toxikologie, Giftinformation, Universitätsklinikum Mainz II. Medizinische Klinik und Poliklinik, Mainz, Germany

    Ludwig Sacha Weilemann

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Eggeling, K., Marth, T. (2016). Zöliakie/Einheimische Sprue. In: Lehnert, H., et al. DGIM Innere Medizin. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-54676-1_337-2

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  • DOI: https://doi.org/10.1007/978-3-642-54676-1_337-2

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  • Online ISBN: 978-3-642-54676-1

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  1. Latest

    Zöliakie/Einheimische Sprue
    Published:
    26 February 2016

    DOI: https://doi.org/10.1007/978-3-642-54676-1_337-2

  2. Original

    Zöliakie/Einheimische Sprue
    Published:
    28 July 2015

    DOI: https://doi.org/10.1007/978-3-642-54676-1_337-1

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