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Daily Routine in Cosmetic Dermatology pp 1–8Cite as

Transepidermal Drug Delivery

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Abstract

The stratum corneum acts as a barrier that limits the penetration of substances through the skin. Transepidermal drug delivery has been developed to increase the penetration of drugs through the superficial layers of the skin. There are many reports about ablative fractional resurfacing creating vertical channels that assist the delivery of topically applied drugs into the skin. The use of nonablative lasers as well as microneedling technique has been reported with the same purpose. In this chapter we are going to discuss some techniques, mechanism of action, and indications.

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Author information

Authors and Affiliations

  1. Universidade Federal Fluminense, Niterói, Brazil

    Maria Claudia Almeida Issa & Livia Roale

  2. São Paulo, Brazil

    Gabriela Casabona

  3. Hospital dos Servidores do Estado do Rio de Janeiro, Rio de Janeiro, Brazil

    Paulo Santos Torreão

Authors
  1. Maria Claudia Almeida Issa
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  2. Gabriela Casabona
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  3. Paulo Santos Torreão
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  4. Livia Roale
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Corresponding author

Correspondence to Maria Claudia Almeida Issa .

Editor information

Editors and Affiliations

  1. Universidade Federal Fluminense, Niterói, São Paulo, Brazil

    Maria Claudia Almeida Issa

  2. Lexbios Medica S/S, São Paulo, São Paulo, Brazil

    Bhertha Tamura

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© 2016 Springer International Publishing AG

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Almeida Issa, M., Casabona, G., Santos Torreão, P., Roale, L. (2016). Transepidermal Drug Delivery. In: Issa, M., Tamura, B. (eds) Daily Routine in Cosmetic Dermatology. Clinical Approaches and Procedures in Cosmetic Dermatology. Springer, Cham. https://doi.org/10.1007/978-3-319-20250-1_31-1

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  • DOI: https://doi.org/10.1007/978-3-319-20250-1_31-1

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  • Publisher Name: Springer, Cham

  • Online ISBN: 978-3-319-20250-1

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