Automotive industry is using increasingly structural bonding in a wider sense. This technology is already commonly used for hoods and doors and for windshield bonding. With the availability of a new generation of structural adhesives for the body shop, these adhesives contribute to build lighter car bodies with increased crash performance. The general requirements for adhesives in automotive production are outlined. The key properties of the various structural adhesives are described and the elements for the evaluation of adhesives with the right properties are mentioned. This chapter serves as a guideline for the evaluation of the right adhesive technology from an engineering point of view and will help to increase the use of this joining method to produce cars which cope with the future challenges for lightweight design.