Reference Work Entry

Encyclopedia of Neuroscience

pp 647-650

Central Pain

  • Troels S. JensenAffiliated withDepartment of Physiology & Biophysics, University of Washington School of MedicineDepartment of Neurology and Danish Pain Research Center, Aarhus University Hospital
  • , Nanna B. FinnerupAffiliated withDepartment of Physiology & Biophysics, University of Washington School of MedicineDepartment of Neurology and Danish Pain Research Center, Aarhus University Hospital

Synonyms

Thalamic pain; Deafferentation pain; Central neuropathic pain

Definition

The International Association for the Study of Pain (IASP) defines neuropathic pain as “Pain initiated or caused by a primary lesion or dysfunction of the peripheral or central nervous system.” A new classification is being introduced by a working group on Neuropathic pain. According to this working group, it is suggested that neuropathic pains are pains arising as a direct consequence of a lesion or disease affecting the somatosensory system. This revised definition fits into the nosology of neurological disorders and also distinguishes neuropathic pain from normal physiological plasticity seen when the somatosensory system is activated following noxious stimulation.

Central Pain (CP) occurs following lesions of the sensory pathways in the spinal cord or brain. The essential pathological feature is a lesion in the CNS resulting in partial or complete loss of sensory input in the nervous sys ...

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