Reference Work Entry

Blaustein’s Pathology of the Female Genital Tract

pp 579-624

Nonneoplastic Lesions of the Ovary

  • Julie A. IrvingAffiliated withDepartments of Gynecology, Obstetrics, Pathology and Oncology, The Johns Hopkins University School of Medicine and Director of Gynecologic Pathology, The Johns Hopkins HospitalDepartment of Laboratory Medicine, Pathology, and Medical Genetics, Royal Jubilee Hospital Email author 
  • , Philip B. ClementAffiliated withDepartment of Pathology and Laboratory Medicine, Weill Cornell Medical College and New York Presbyterian HospitalDepartment of Pathology, Vancouver Hospital and Health Sciences Center


Nonneoplastic lesions of the ovary frequently form a pelvic mass and are often associated with abnormal hormonal manifestations, thus potentially mimicking an ovarian neoplasm on clinical examination, at operation, or on pathologic examination. Many occur in the reproductive years and may be associated with infertility. Their proper recognition is, therefore, important to allow appropriate, usually conservative therapy, thereby avoiding unnecessary oophorectomy. This chapter begins with a very brief overview of the embryology and gross anatomy of the normal ovary, and key aspects of normal ovarian histology are featured in the discussion of relevant nonneoplastic lesions.