Reference Work Entry

Blaustein’s Pathology of the Female Genital Tract

pp 453-527

Mesenchymal Tumors of the Uterus

  • Charles J. ZaloudekAffiliated withDepartments of Gynecology, Obstetrics, Pathology and Oncology, The Johns Hopkins University School of Medicine and Director of Gynecologic Pathology, The Johns Hopkins HospitalDepartment of Pathology, University of California, San Francisco Email author 
  • , Michael R. HendricksonAffiliated withDepartment of Pathology and Laboratory Medicine, Weill Cornell Medical College and New York Presbyterian HospitalDepartment of Surgical Pathology, Stanford University Medical Center
  • , Robert A. SoslowAffiliated withDepartment of Pathology, Johns Hopkins University School of MedicineDepartment of Pathology, Memorial Sloan-Kettering Cancer Center


This chapter deals with neoplasms of the uterus in which there is mesenchymal differentiation. Purely mesenchymal tumors, such as those derived from smooth muscle and endometrial stroma, are considered, as are some benign and malignant neoplasms in which there are mixtures of epithelium and connective tissues. We use a slightly modified version of the comprehensive classification of mesenchymal neoplasms of the uterus, developed by the World Health Organization (WHO; [409]) which is shown in Table 10.1 .