Reference Work Entry

Encyclopedia of Genetics, Genomics, Proteomics and Informatics

pp 248-248

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Cachectin

A hormone-like protein product of the macrophages which releases fat and lowers the concentration of fat synthetic and storage enzymes. It is encoded by a gene situated within the HLA cluster in human chromosome 6p21.3. HLA, macrophage; Jue DM et al 1990 Biochemistry 29:8371.

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