Reference Work Entry

Encyclopedia of Genetics, Genomics, Proteomics and Informatics

pp 2058-2058



Includes gene neighborhoods where individual operons may show rearrangement in different species, yet remain in the functional and regulatory context (Lathe WC III et al 2000 Trends Biochem Sci 25:474). Rogozin and associates (Rogozin IB et al 2002 Nucleic Acids Res 30:2212) named this phenomenon genome hitchhiking. The largest such neighborhood in prokaryotes includes 79 genes. Most, albeit not all these genes, share a known functional role. operon, supraoperon

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