Rare (∼3 × 10−4) abnormal chromosomes with internal duplications and deletions. The majority (∼60%) involves two inverted copies of the short arm, centromere and the proximal segment of the long arm of human chromosome 15 (SMC). The majority of the latter are dicentric but one of the centromeres is inactive (pseudocentromeric 15). chromosomal rearrangements; Roberts SE et al 2003 Am J Hum Genet 73:1061.
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