Positive-Strand Virus

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The genome of a positive-strand virus is also a mRNA. Upon transcription, the virus may directly produce an infectious nucleic acid. This is a very large class of RNA viruses including the Brome Mosaic Virus, the Hepatitis C Virus, West Nile Virus, Corona Viruses, etc. Their replication is affected by at least 100 genes (Kushner DB et al 2003 Proc Natl Acad Sci USA 100:15764). replicase, plus strand, mRNA, negative strand virus