Reference Work Entry

Encyclopedia of Genetics, Genomics, Proteomics and Informatics

pp 1399-1399

Operational RNA Code

This is a sequence/structure-dependent aminoacylation of RNA oligonucleotides that are devoid of an anticodon. The specificity and efficiency is determined by a few nucleotides near the amino acid acceptor arm. aminoacylation, aminoacyl-tRNA synthetase, transfer RNA, minihelix of tRNA; Schimmel P et al 1993 Proc Natl Acad Sci USA 90:8763; de Pouplana LR, Schimmel P 2001 J Biol Chem 276:6881.

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